Results 171 to 180 of about 388 (231)

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

open access: yesMedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Deciphering the Presence of Active Interscapular Brown Adipose Tissue in Humans

open access: yesActa Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Brown adipose tissue (BAT) is increasingly recognized as a metabolically active tissue in humans, although its physiological relevance remains incompletely understood. In rodents, BAT is well characterized, with interscapular BAT (iBAT) representing the main thermogenic depot.
Joaquin Sanchez‐Gomez   +8 more
wiley   +1 more source

Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 7, Page 1578-1601, April 2026.
Background and Purpose Human adenovirus (HAdV) causes respiratory or gastrointestinal tract infections depending on the virus subtype. While HAdV infections are generally self‐limiting in immunocompetent people, they can result in significant morbidity and mortality in immunocompromised adults and children.
Mohamed Zamzamy   +16 more
wiley   +1 more source

Rationale and design of a parallel randomised trial of a plant‐based intensive lifestyle intervention for diabetes remission: The REmission of diabetes using a PlAnt‐based weight loss InteRvention (REPAIR) trial

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2627-2641, April 2026.
Abstract Aims As type 2 diabetes (T2D) continues to rise globally and remains a major driver of cardiovascular disease, its remission has emerged as a therapeutic target. Current evidence supports bariatric surgery and low‐calorie diets with meal replacements.
Brighid McKay   +19 more
wiley   +1 more source

Wellness testing in blood donation: A framework for responsible innovation

open access: yes
Transfusion, EarlyView.
Jeremy W. Jacobs   +5 more
wiley   +1 more source

Stories From Black Women in Iowa About Reproductive Health Care Experiences, Self‐Advocacy, and Recommendations for Change

open access: yesHealth Expectations, Volume 29, Issue 2, April 2026.
ABSTRACT Research Question What are Black women's experiences when seeking reproductive health care in Iowa? Design Narrative‐style qualitative research. Methods Adult Black women in Iowa were recruited for phone interviews. Data was analysed using within and across case methodology.
Melissa Lehan. Mackin   +5 more
wiley   +1 more source

Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review

open access: yesInternational Journal of Dermatology, Volume 65, Issue 4, Page 706-723, April 2026.
ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska   +8 more
wiley   +1 more source

The Dual Immunoregulatory Role of CREB3L1 Underlying Latent and Severe Tuberculosis Clinical Manifestation

open access: yesImmunology, Volume 177, Issue 4, Page 810-823, April 2026.
RNA‐seq of lungs and livers from Mycobacterium tuberculosis ‐infected mice with distinct disease outcomes revealed organ‐specific responses driven by differences in immune activity and bacterial burden. Meta‐analysis identified orthologous genes shared with human latent TB and mouse liver, with Creb3l1, Myo7b, Cyyr1 and Cbs differentially expressed and
Felipe T. Lima   +9 more
wiley   +1 more source

Practices in the prescription of antiseizure medications: is it time to change? [PDF]

open access: yesArq Neuropsiquiatr
Pinto LF   +5 more
europepmc   +1 more source

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