Results 201 to 210 of about 388 (231)
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Natural Products as Anti-HIV Agents
1992The publication, in 1981, of a report announcing the occurrence of a cluster of diagnoses of a rare form of pneumonia due to the microorganism Pneumocystis carinii in a group of male homosexuals in San Francisco constitutes the first notice of the advent of a new disease. It was quickly recognized, subsequent to that report, that the occurrence of this
Daniel Lednicer, Ven L. Narayanan
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Researchers Explore New Anti-HIV Agents
JAMA, 2002SEATTLE—While antiretroviral drugs have done much to extend the lives of people infected with HIV, severe adverse effects and rising levels of drug resistance can limit their usefulness and are driving efforts to develop new antiHIV medications. Building on knowledge of HIV gleaned from laboratory studies of the virus, researchers are developing and ...
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Antisense Oligonucleotide as Anti-HIV Agents.
Kobunshi, 1993アンチセンスRNA/DNAを利用した医薬品開発の一つとして,エイズの原因であるHIVの感染,増殖抑制作用をもつオリゴマーの合成とin vitro試験での活性評価を行った.結果,rev,tat遺伝子に相補的なphosphorothioate型オリゴDNAが強い抗HIV活性を示すことを確認した.今後,詳細な作用機序や代謝機構が明確にされることで,治療薬としての位置付けが確立されるであろう.
Hideki Nakashima, Naoki Yamamoto
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[Anti-HIV-1 p17 antibody as anti-HIV agent].
Nihon rinsho. Japanese journal of clinical medicine, 1994H, Tsuchie +3 more
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Current Status of Anti-HIV Agents
Current Medicinal Chemistry -Anti-Infective Agents, 2005V. Tandon, R. Chhor
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[Polyphenols as anti-HIV agents].
Nihon rinsho. Japanese journal of clinical medicine, 1994H, Sakagami, M, Takeda
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