Results 221 to 230 of about 1,841,120 (284)

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Microbiota and Methylglyoxal-Derived AGEs: Implications in Ageing and Age-Related Disease. [PDF]

Life (Basel)
Tombolesi N, Francini E, Badillo-Pazmay GV, Fortunato C, Marchegiani F, Olivieri F, Fumarola S, Maniscalco R, Matacchione G.   +8 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Correction to "Cascading Periods of Language-Related Brain Plasticity across Early Childhood". [PDF]

Dev Sci
europepmc   +1 more source

Defining Age to Screen and Real-World Effectiveness for Early-Onset Colorectal Cancer. [PDF]

Cancer Sci
Wang L, Qiu Y, Chen X, Wu W, Zhu C, Chen W, Pan T, Hang D, Du L.   +8 more
europepmc   +1 more source

Mental health and health behaviours in adolescence and risk of being NEET from ages 16 to 24: longitudinal findings from the UKHLS

Li Z, Wels J, Chaturvedi N, Patalay P.
europepmc   +1 more source

Cost-benefit analysis of universal pool fencing for Texas households with young children. [PDF]

Inj Epidemiol
Rhodes J, Nguyen L, Shenoi RP.
europepmc   +1 more source

Serum Advanced Glycation End Products as Drivers of Poor Tendon Outcomes in Diabetes? An Emerging Hypothesis and Narrative Review. [PDF]

Endocrinol Diabetes Metab
Gutierrez EJ, Mitevski LE, Haus JM, Carroll CC.   +3 more
europepmc   +1 more source

Herpes zoster frequency and severity in immunocompromised pediatric populations: a structured narrative review. [PDF]

Front Pediatr
Simpson C, Viscidi E, Gadoth A.
europepmc   +1 more source