Targeting MAN1B1 potently enhances bladder cancer antitumor immunity via deglycosylation of CD47
Cancer Communications, EarlyView.Abstract Background Only a few bladder cancer patients benefit from anti‐programmed cell death protein 1/programmed cell death ligand 1 immunotherapy. The cluster of differentiation 47 (CD47) plays an important role in tumor immune evasion. CD47 is a highly glycosylated protein, however, the mechanisms governing CD47 glycosylation and its potential ...
Jie Zhang +20 more
wiley +1 more source
Lectins with Anti-HIV Activity: A Review
Molecules, 2015 Lectins including flowering plant lectins, algal lectins, cyanobacterial lectins, actinomycete lectin, worm lectins, and the nonpeptidic lectin mimics pradimicins and benanomicins, exhibit anti-HIV activity.
Ouafae Akkouh +7 more
doaj +1 more source
Localization of axonally transported 125I-wheat germ agglutinin beneath the plasma membrane of chick retinal ganglion cells. [PDF]
, 1983 The distribution of 125I-wheat germ agglutinin (WGA) transported by axons of chick retinal ganglion cells to layer d of the optic tectum was studied by electron microscopic autoradiography.
LaVail, JH, McDonald, DM, Sugino, IK
core
Giardia Cyst Wall Protein 1 Is a Lectin That Binds to Curled Fibrils of the GalNAc Homopolymer [PDF]
, 2010 The infectious and diagnostic stage of Giardia lamblia (also known as G. intestinalis or G. duodenalis) is the cyst. The Giardia cyst wall contains fibrils of a unique β-1,3-linked N-acetylgalactosamine (GalNAc) homopolymer and at least three cyst wall ...
Bullitt, Esther +6 more
core +4 more sources
Recent Advances in Understanding the Sex Pheromone‐Mediated Communication of Diatoms
ChemPlusChem, EarlyView.Pheromones control the sexuality and mate finding in diatoms, a group of highly abundant unicellular marine algae. The diatom pheromones presented here are elucidated using a metabolomics‐based approach. This review introduces new structures, methods, and conceptual advances and discusses future perspectives in diatom research.
Franziska Alessandra Klapper +1 more
wiley +1 more source
Advanced Imaging and Cytometric Techniques to Characterize Lipid Accumulation in Wolman Disease
Cytometry Part A, EarlyView.ABSTRACT Wolman disease (WD) is a severe lysosomal storage disorder characterized by fatal lipid accumulation caused by the deficiency of a lipid metabolic enzyme, Lysosomal Acid Lipase (LAL), involved in the lysosomal hydrolysis of cholesterols and triglycerides.
Marine Laurent +9 more
wiley +1 more source
Purification and properties of a plant Agglutinin [PDF]
, 1958 Thesis (M.A.)--Boston UniversityThis study involved work with extracts of the seeds of Bauhinia purpurea alba, in which an N specific lectin was found by Mäkelä (37) and Boyd and McMaster (16). There were two main purposes in mind.
Everhart, Donald Lee
core +1 more source
Glycotope structures and intramolecular affinity factors of plant lectins for Tn/T antigens [PDF]
, 2011 B
A Babino +42 more
core +3 more sources
The purification, composition and specificity of wheat-germ agglutinin.
Biochemical Journal, 1973 1. The purification of wheat-germ agglutinin from commercial wheat germ is described. By ion-exchange chromatography three active proteins (isolectins) were separated, one of which was examined in detail. 2.
A. K. Allen, A. Neuberger, N. Sharon
semanticscholar +1 more source
Intestinal Barrier Glycosylation for Gut Physiology and Pathology
Barrier Immunity, EarlyView.ABSTRACT The intestinal barrier is a selective structure that safeguards the body from external threats while permitting nutrient absorption and immune surveillance. It consists of the outer mucus layer, the intermediate layer of intestinal epithelial cells (IECs), and the inner layer of immune cells. The proteins in the mucus layer and within IECs are
Girak Kim, Deji Ye, Yikun Yao, Chuan Wu
wiley +1 more source