Results 151 to 160 of about 53,061 (292)

Hevin Promotes Aging‐Related Cardiac Dysfunction via Facilitating Cardiac Inflammation in Male Mice

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Hevin released by iWAT into circulation stimulates cardiac macrophages through TLR4, inducing their polarization and CCL5 secretion, leading to worsened cardiac dysfunction and subsequent recruitment of additional inflammatory cells for pro‐inflammatory factor release.
Shi‐Yu Huang   +4 more
wiley   +1 more source

Context‐Dependent Roles of ANGPTL2‐Mediated Inflammaging in Tissue Homeostasis, Pathological Tissue Remodeling, and Longevity

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Yumoto et al. show that ANGPTL2 regulates inflammation, fibrosis, and tissue remodeling in high‐fat diet‐induced premature aging. ANGPTL2 deficiency shortens lifespan but reduces inflammation, revealing its context‐dependent and organ‐specific roles in maintaining homeostasis.
Shinsei Yumoto   +8 more
wiley   +1 more source

Distinct Roles of SLC26A3 and CFTR in Surface pH Regulation and Bicarbonate Secretion in Human Intestinal Epithelium

open access: yesActa Physiologica, Volume 242, Issue 2, February 2026.
ABSTRACT Background and Aims Colonic bicarbonate secretion is mediated by the chloride/bicarbonate exchanger SLC26A3 and the cystic fibrosis transmembrane conductance regulator (CFTR). Dysfunction of either causes luminal acidosis, altered mucus properties, and inflammation.
Mahdi Amiri, Azam Salari, Ursula Seidler
wiley   +1 more source

Gut mucin fucosylation dictates the entry of botulinum toxin complexes. [PDF]

open access: yesNat Commun
Amatsu S   +12 more
europepmc   +1 more source

Cryoglobulinemia: An update on classification, pathophysiology, clinical presentation, and management

open access: yesJournal of Internal Medicine, Volume 299, Issue 2, Page 196-215, February 2026.
Abstract Cryoglobulinemia (CG) is defined by the presence of serum immunoglobulins that precipitate below 37°C and redissolve upon rewarming. It is classified into three types based on immunoglobulin composition. Type I, a rare form, involves monoclonal IgM or IgG and is linked to lymphoproliferative disorders.
Anna Linda Zignego   +7 more
wiley   +1 more source

Smart Nanogels as Enzyme‐Driven Nanomotors for Navigating Viscous Physiological Barriers

open access: yesAdvanced Functional Materials, Volume 36, Issue 2, 5 January 2026.
Two families of urease‐powered nanomotors (NMs), with and without a p‐(2‐hydroxyethyl methacrylate) (p‐HEMA) shell, have been successfully prepared. Both types exhibit effective motion in highly viscous synovial fluid media at low urea concentrations (25 mM).
David Esporrín‐Ubieto   +6 more
wiley   +1 more source

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