Results 81 to 90 of about 53,061 (292)
Small Methods, EarlyView.This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto +12 more
wiley +1 more source
Can We Really Believe This Platelet Count?
American Journal of Hematology, EarlyView.
James Manning +3 more
wiley +1 more source
Detection of Leptospira in cane toads (Rhinella jimi) from urban and rural Paraíba, Brazil
Veterinary Record, EarlyView.Abstract Background Leptospirosis is a significant zoonosis in tropical regions, where poor sanitation and favourable climate aid its spread. Synanthropic animals such as the cane toad (Rhinella jimi), which share environments with both people and wild and domestic animals, may harbour Leptospira and contribute to urban and rural transmission cycles ...
Karla N. de Souza Rocha +9 more
wiley +1 more source
Chemical dehydration‐induced ultrafast clearing method for human tissues
VIEW, EarlyView.Three‐dimensional (3D) histology of human tissue through clearing has been hampered by the lengthy and intricate procedure. Here, a rapid and straightforward clearing protocol termed single‐step dehydration solvent‐based clearing (SSD) is proposed via a chemical dehydration strategy.
Yi Dai +16 more
wiley +1 more source
Andrology, EarlyView.Abstract Background Energy metabolism and substrate balance are critical determinants of sperm motility and fertility. Linear motility is necessary for sperm forward movement, whereas hyperactivated motility is a prerequisite for fertilization. The preference of metabolic pathways depends on substrate availability which controls sperm motility. However,
Md Faizul Hossain Miraz +4 more
wiley +1 more source
Impact of Sorting and Catch Media on Porcine Sperm Motility, Capacitation, and Viability
Andrology, EarlyView.ABSTRACT Background Fluorescence‐activated cell sorting (FACS) has emerged as a powerful tool for selecting spermatozoa of a desired population of fluorescent biomarkers, offering potential applications in reproductive biology and agriculture. However, concerns remain regarding sorting‐induced physiological alterations that could compromise spermatozoa
Tyler Weide, Juan Steibel, Karl Kerns
wiley +1 more source
Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway
British Journal of Pharmacology, EarlyView.Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu +4 more
wiley +1 more source
SAGE Open Medical Case ReportsCold agglutinin-induced hemolytic anemia presents diagnostic and management challenges, particularly in resource-limited settings like Pakistan. A 92-year-old male presented with altered consciousness, fever, weakness, and severe asthenia.
Ayesha Amjad +3 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi +19 more
wiley +1 more source
Differential involvement of cell surface sialic acid residues in wheat germ agglutinin binding to parental and wheat germ agglutinin-resistant Chinese hamster ovary cells. [PDF]
, 1980 Pamela Stanley, T Sudo, J. P. Carver
openalex +1 more source