Results 51 to 60 of about 642,146 (342)
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Production Planning and Aggregate Production Planning
, 2017 Competition has a direct impact on the growth of the economy. Manufacturing systems can be improved by a well-thought-out production strategy. Problems with aggregate production planning and sales forecasting are leading an Installation Elevator Company to be unable to deliver items on time and have an impact on customer satisfaction.
openaire +1 more source
, 2020 It is widely felt that the performance evaluation in aggregate production planning provides a theoretical and practical overview. The present study aimed to evaluate the performance in the aggregate production planning. In this regard, the optimal values
Javad Khalili, A. Alinezhad
semanticscholar +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Logistics Research, 2016 In this work the influence of production and capacity planning on decisions regarding facility location, distribution quantities and component remanufacturing (and vice versa) in a closed-loop supply chain network (CLSCN) with multiple make-to-order ...
Leena Steinke, Kathrin Fischer
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Un modelo de optimización para planificar la producción de una compañía siderúrgica
Ingenieria Industrial, 2009 En este trabajo se resuelve un problema de planificación agregada de la producción de Compañía Siderúrgica Huachipato S.A., a través de un modelo de programación lineal. La planificación agregada de la producción es a mediano plazo, en donde se considera
Felipe Alvarez Clifford +1 more
doaj
Production, staff, working time and financial planning
Intangible Capital, 2009 Aggregate planning can be a tool for coordinating the tactical decisions belonging to some functional areas of a company. This potential has been limited due to methodological and technical reasons, but nowadays it is possible to solve very sophisticated
Orlando Boiteux +3 more
doaj +1 more source