Results 51 to 60 of about 8,534,336 (300)
Production planning of biopharmaceutical manufacture. [PDF]
, 2006 Multiproduct manufacturing facilities running on a campaign basis are increasingly becoming the norm for biopharmaceuticals, owing to high risks of clinical failure, regulatory pressures and the increasing number of therapeutics in clinical evaluation ...
Lakhdar, K.
core
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Algorithms, 2022 Due to the influence of insufficient production capacity or shortage of production materials, production enterprises may produce products in advance or be backordered.
Lanfen Liu, Xinfeng Yang
doaj +1 more source
AGGREGATE PLANNING IN PRODUCTION AND SERVICE ENTERPRISES : Graduate paper
, 2022 Svrha agregatnog planiranja je prikaz cjelokupne slike unutar proizvodnje, odnosno proizvodnja proizvoda u određenom vremenskom periodu, također agregatno planiranje daje uvid u organizaciju svih raspoloživih resursa.
Benković, Luka
core +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Un modelo de optimización para planificar la producción de una compañía siderúrgica
Ingenieria Industrial, 2009 En este trabajo se resuelve un problema de planificación agregada de la producción de Compañía Siderúrgica Huachipato S.A., a través de un modelo de programación lineal. La planificación agregada de la producción es a mediano plazo, en donde se considera
Felipe Alvarez Clifford +1 more
doaj
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Targeting Aggregate Production Planning for an Energy Supply Chain
, 2015 Aggregate production planning for an energy supply chain is presented in this paper. The methodology is equally applicable to aggregate production planning of production as well as aggregate planning Of input material supply. The proposed.
BANDYOPADHYAY, S, CHATURVEDI, ND
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source