Results 51 to 60 of about 20,398 (300)

AGGREGATE PLANNING IN PRODUCTION AND SERVICE ENTERPRISES : Graduate paper

, 2022
Svrha agregatnog planiranja je prikaz cjelokupne slike unutar proizvodnje, odnosno proizvodnja proizvoda u određenom vremenskom periodu, također agregatno planiranje daje uvid u organizaciju svih raspoloživih resursa.
Benković, Luka
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Un modelo de optimización para planificar la producción de una compañía siderúrgica

Ingenieria Industrial, 2009
En este trabajo se resuelve un problema de planificación agregada de la producción de Compañía Siderúrgica Huachipato S.A., a través de un modelo de programación lineal. La planificación agregada de la producción es a mediano plazo, en donde se considera
Felipe Alvarez Clifford, Hernaldo Reinoso   +1 more
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Optimization of aggregate planning of variant production processes

, 2022
In the conventional approach to aggregate planning, alternative production routes (i.e. variants) using different machines are hardly ever considered.
Schulte, J., Roth, H.P., Dangelmaier, W.
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Aggregate Production Planning for Cost Optimization: A Case Study of Van’z Collection, a Small-Scale Garment Manufacturer

Society
This study aims to evaluate the aggregate production planning system and explore alternative aggregate strategies to improve cost efficiency in the production planning process.
Zahra Nur Afifah, Ayi Tejaningrum
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

An Icon-Based Methodology for the Design of a Prototype of a Multi-Process, Multi-Product, Aggregated Production Planning Software

Mathematics
This paper proposes an icon-based methodology for the design of prototype aggregated production planning software that addresses the complexity of multi-process and multi-product production. Aggregate planning is a critical task in production management,
Erick Miranda-Meza, Iván Derpich, Juan M. Sepúlveda   +2 more
doaj   +1 more source