Results 91 to 100 of about 5,001,808 (350)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Measuring Forecast Uncertainty by Disagreement: The Missing Link [PDF]
Using a standard decomposition of forecasts errors into common and idiosyncratic shocks, we show that aggregate forecast uncertainty can be expressed as the disagreement among the forecasters plus the perceived variability of future aggregate shocks ...
Kajal Lahiri, Xuguang Sheng
core +3 more sources
Aggregates of rod-coil diblock copolymers adsorbed at a surface
The behaviour of rod-coil diblock copolymers close to a surface is discussed by using extended scaling methods. The copolymers are immersed in selective solvent such that the rods are likely to aggregate to gain energy. The rods are assumed to align only
C. Nowak +3 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Influence of aggregate gradation on hma mixes stability
The load transfer capacity of pavements is to a great extend influenced by aggregates. About 85% of the total volume of hot mix asphalt (HMA) mixtures consists of aggregates; thus, they are greatly influenced by aggregate properties like angularity ...
Kalaitzaki Elvira +2 more
doaj +1 more source
A dynamic econometric study of income, energy and exports in Turkey [PDF]
This study attempts to examine empirically dynamic causal relationships between aggregate output, energy consumption, exports, capital and labour in the case of Turkey using the time series data for the period 1968-2008.
Halicioglu, Ferda
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Aggregate stability in soils cultivated with eucalyptus. [PDF]
The objective of this work was to evaluate the aggregate stability of tropical soils under eucalyptus plantation and native vegetation, and assess the relationships between aggregate stability and some soil chemical and physical properties.
AVANZI, J. C. +5 more
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