Results 121 to 130 of about 4,583,324 (336)

Effects of Freeze–Thaw Cycles on Soil Aggregate Stability and Organic Carbon Distribution Under Different Land Uses

open access: yesAgriculture
Soil aggregates are critical determinants of soil erosion resistance and nutrient retention capacity, while freeze–thaw cycles (FTCs) induce the structural reorganization of soil aggregates, thereby altering soil stability and influencing soil organic ...
Yuting Cheng   +5 more
doaj   +1 more source

Temporal changes in wet aggregate stability [PDF]

open access: yes, 1992
Aggregate stability, a property that influences a soil's erodibility and hydraulic characteristics, has been shown in previous investigations (e.g., Bullock et al., 1988) to vary over time for some northwestern U.S. soils.
Lehrsch, G.A.   +3 more
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The Aggregate Demand, Aggregate Supply, and Endogenous Growth: A Synthetic neo-Kaleckian Model [PDF]

open access: yes
This paper develops a neo-Kaleckian endogenous growth model that incorporates aggregate supply - demand balance and balance between labor force and employment growth.
Thomas I. Palley
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Stability and bounds in aggregate scheduling networks

open access: yes, 2008
We study networks of FIFO nodes, where flows are constrained by arrival curves. A crucial question with these networks is: Can we derive a bound to the maximum delay that a packet can experience when traversing the network, and to the maximum queue size at each node?
openaire   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

On the stability of utilitarian aggregation

open access: yes
In the context of aggregating von Neumann-Morgenstern utilities, we show that bounded violations of the Pareto conditions characterize aggregation rules that are approximately utilitarian. When a single utility function is intended to represent the preference judgments of a group of individuals and the Pareto principles are nearly satisfied, we prove ...
openaire   +2 more sources

Assessing Romanian financial sector stability: the importance of the international economic climate

open access: yes
The aim of this paper is to develop an aggregate stability index for the Romanian financial system. The index which is meant to enhance the set of analysis used by the central bank to assess the financial stability accurately reflects the financial ...
Albulescu, Claudiu Tiberiu
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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