Results 61 to 70 of about 10,935 (240)

Aggregatibacter actinomycetemcomitans Leukotoxin [PDF]

Journal of Dental Research, 2010
Aggregatibacter actinomycetemcomitans is a Gram-negative bacterium that colonizes the human oral cavity and is the causative agent for localized aggressive periodontitis (LAP), an aggressive form of periodontal disease that occurs in adolescents. A. actinomycetemcomitans secretes a protein toxin, leukotoxin (LtxA), which helps the bacterium evade the ...
openaire   +2 more sources

Does timing of systemic antibiotics influence periodontal treatment outcomes? A randomized clinical trial

Journal of Periodontology, EarlyView.
Abstract Background The aim of this study is to determine whether the timing of metronidazole (MTZ) and amoxicillin (AMX) administration, relative to scaling and root planing (SRP), influences the clinical and microbiological outcomes of periodontal treatment.
Daiane Fermiano, Eduardo de Souza Oliveira, Maria Josefa Mestnik, Luciene C. Figueiredo, Takahiko Shiba, Shunsuke Matsumura, Edson de Sousa, Helio Doyle, Rafael Oliveira Dias, Marcelo de Faveri, Magda Feres   +10 more
wiley   +1 more source

Effects of Aggregatibacter actinomycetemcomitans leukotoxin on endothelial cells

Microbial Pathogenesis, 2013
Aggregatibacter actinomycetemcomitans is a human pathogen that produces leukotoxin (LtxA) as a major virulence factor. In this study the effect of LtxA on microvascular endothelial cell viability and phenotype was studied. High doses of single LtxA treatment (500 ng/ml to 5 μg/ml) significantly and irreversibly decreased cell proliferation and induced ...
Dietmann, Anelia, Millonig, Alban, Combes, Valery, Couraud, Pierre-Olivier, Kachlany, Scott C., Grau, Georges E.   +5 more
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Effects of Aggregatibacter actinomycetemcomitans leukotoxin on neutrophil migration and extracellular trap formation.

, 2016
BACKGROUND: Aggressive periodontitis is associated with the presence of Aggregatibacter actinomycetemcomitans, a leukotoxin (Ltx)-producing periodontal pathogen. Ltx has the ability to lyse white blood cells including neutrophils.
Hirschfeld, Josefine, Parčina, Marijo, Johansson, Anders, Jepsen, Søren, Claesson, Rolf, Claesson, Rolf,, Helen M. Roberts, Josefine Hirschfeld, Roberts, Helen M, Rolf Claesson, Johansson, Anders,, Anders Johansson, Chapple, Iain L C, Iain L. C. Chapple, Marijo Parčina, Søren Jepsen   +15 more
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Mechanical Valve Endocarditis and Dehiscence from Aggregatibacter actinomycetemcomitans Bacteremia

Brown Journal of Hospital Medicine, 2023
HACEK are gram negative organisms that are typically part of the oropharyngeal flora and are responsible for 1-3% of infective endocarditis cases. We describe an instance of multivalvular endocarditis caused by Aggregatibacter actinomycetemcomitans ...
Jerry Fan, Corry Sanford, Billy Don Jones   +2 more
doaj  

Electrolyzed saline as an alternative to chlorhexidine: Antimicrobial and biofilm volume outcomes in a 4‐day non‐brushing randomized controlled clinical trial

Journal of Periodontology, EarlyView.
Abstract Background The biofilm‐inhibitory effects of electrolyzed saline (EOS) vary widely due to differences in formulations and treatment methods. This study analyzed the impact of EOS on key oral microbial species and used serial 3D‐intraoral scans to evaluate its effects on de novo biofilm formation.
Katja Povšič, Haris Munjaković, Naiera Zayed, Wim Teughels, Katja Seme, Aleš Fidler, Rok Gašperšič   +6 more
wiley   +1 more source

The cell envelope proteome of Aggregatibacter actinomycetemcomitans [PDF]

Molecular Oral Microbiology, 2014
SummaryThe cell envelope of gram‐negative bacteria serves a critical role in maintenance of cellular homeostasis, resistance to external stress, and host–pathogen interactions. Envelope protein composition is influenced by the physiological and environmental demands placed on the bacterium.
K P, Smith, J G, Fields, R D, Voogt, B, Deng, Y-W, Lam, K P, Mintz   +5 more
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Impact of severe periodontitis and diabetes mellitus on recurrent cardiovascular outcomes

Journal of Periodontology, EarlyView.
Abstract Background This post hoc analysis of the Periodontitis and Coronary Heart Disease study (ClinicalTrials.gov Identifier: NCT01045070) aimed to determine the association between diabetes and recurrent cardiovascular events (CVEs) in patients with cardiovascular disease (CVD) and severe periodontitis.
Stefan Reichert, Axel Schlitt, Selina Rehm, Susanne Schulz   +3 more
wiley   +1 more source

Antimicrobial susceptibilities of Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis strains from periodontitis patients in Morocco

, 2019
Background and objective: Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis have been frequently isolated in periodontitis patients in Morocco.
Ennibi, Oumkeltoum, Perdiguero Jiménez, Pedro, Lakhdar, Leila, Abdellaoui, Lamia, Sanz Alonso, Mariano, Mínguez, María, Sánchez Beltrán, María Del Carmen, Herrera González, David   +7 more
core   +1 more source

Anti-adherence potential of immunoglobulin Y Aggregatibacter actinomycetemcomitans against Aggregatibacter [PDF]

, 2020
Aggregatibacter actinomycetemcomitans is the main cause of aggressive periodontitis. Immunoglobulin Y (Ig Y) is the main antibody in poultry, reptiles, lungfish and can be found in chicken egg yolk.
Rini Devijanti Ridwan, Sakawa Kanni, Indeswati Diyatri   +2 more
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