Results 71 to 80 of about 78,642 (289)

Aggregation induced emission by pyridinium–pyridinium interactions

RSC Advances, 2019
Non-covalent intermolecular pyridinium–pyridinium and pyridinium–arene-π system interactions result in aggregation induced emission (AIE).
Kaspars Leduskrasts, Edgars Suna
openaire   +3 more sources

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

AIEgen configuration transition and aggregation enable dual prompt emission for single‐component nondoped white OLEDs

Aggregate
The dual emission (DE) feature in materials holds great potential to revolutionize the development of one‐component system white organic light‐emitting diodes (WOLEDs). However, the reported DE materials remain scarce owing to the formidable challenge of
Jiasen Zhang, Qiang Wei, Wei Li, Hao Chen, Xiangyu Zhu, Yongqi Bai, Nannan Fei, Liang Cao, Zujin Zhao, Anjun Qin, Ben Zhong Tang, Ziyi Ge   +11 more
doaj   +1 more source

Tetraarylethene fluorescent dyes with aggregation-induced emission for LED-driven photocuring and 3D printing

, 2022
Dongxiao Li, Yimei Liu, Binghui Bao, Yao Du, Jian You, Luhang Zhang, Haitao Zhan, Mingyang Li, Tao Wang   +8 more
openalex   +2 more sources

Simultaneous Photodynamic Eradication of Tooth Biofilm and Tooth Whitening with an Aggregation‐Induced Emission Luminogen [PDF]

, 2022
Meijia Gu, Susu Jiang, Xiaoyu Xu, Mingyu Wu, Chao Chen, Yuncong Yuan, Qingrong Chen, Yidan Sun, Luojia Chen, Chao Shen, Peng Guo, Shujie Liu, Engui Zhao, Shi Chen, Sijie Chen   +14 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Highly specific characterization and discrimination of monosodium urate crystals in gouty arthritis based on aggregation-induced emission luminogens [PDF]

, 2023
Wenjuan Wang, Guiquan Zhang, Ziyi Chen, Hanlin Xu, Bohan Zhang, Rong Hu, Anjun Qin, Yinghui Hua   +7 more
openalex   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source