Results 51 to 60 of about 78,685 (258)
Aggregation-Induced Emission (AIE), Life and Health
ACS Nano, 2023 Light has profoundly impacted modern medicine and healthcare, with numerous luminescent agents and imaging techniques currently being used to assess health and treat diseases. As an emerging concept in luminescence, aggregation-induced emission (AIE) has shown great potential in biological applications due to its advantages in terms of brightness ...
Haoran Wang +88 more
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Aggregation‐induced emission systems involving supramolecular assembly
Aggregate, 2020 Aggregation‐induced emission (AIE), as an exciting photophysical phenomenon, has been regarded as one frontier research topic within both ranges of molecular luminescence and materials science over the last two decades.
Xin‐Yue Lou, Ying‐Wei Yang
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Aggregation induced emission by pyridinium–pyridinium interactions
RSC Advances, 2019 Non-covalent intermolecular pyridinium–pyridinium and pyridinium–arene-π system interactions result in aggregation induced emission (AIE).
Kaspars Leduskrasts, Edgars Suna
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Visualization of supramolecular assembly by aggregation‐induced emission
Aggregate, 2023 Supramolecular architectures are constructed by the self‐assembly of small building blocks via the use of metal‐ligand coordination, π–π stacking interactions, hydrogen bonding, host‐guest interactions, and other noncovalent driving forces, which confer ...
Wu‐Jie Guo +7 more
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
AggregateFluorescent lateral flow immunoassay (LFIA) has emerged as a critical point‐of‐care (POC) diagnostic platform for in vitro diagnosis. However, the analytical sensitivity of conventional fluorescent LFIA is constrained by the suboptimal quantum yield (QY)
Yaxin Hu +6 more
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Materials Today BioVacuoles are unique organelles of fungi. The development of probes targeting the vacuoles membrane will enable visualization of physiological processes and precise diagnosis and therapy.
Bingnan Wang +10 more
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