Results 51 to 60 of about 869,286 (298)

Linguistic interval 2-tuple power aggregation operators and their applications [PDF]

International Journal of Computational Intelligence Systems, 2013
In this paper, we present a linguistic interval 2-tuple representation model and new linguistic interval 2-tuple aggregation operators, i.e., linguistic interval 2-tuple power average (LI2TPA) operator, linguistic interval 2-tuple weighted power average (
Yanli Ruan, Zheng Pei, Zhisheng Gao
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A Bibliometric Review of the Ordered Weighted Averaging Operator

Mathematics
The ordered weighted averaging (OWA) operator was proposed by Yager back in 1988 and constitutes a parameterized family of aggregation functions between the minimum and the maximum.
Anton Figuerola-Wischke, José M. Merigó, Anna M. Gil-Lafuente, Josefa Boria-Reverter   +3 more
doaj   +1 more source

An Approach to Multiple Attribute Group Decision Making Based on Intuitionistic Trapezoidal Fuzzy Power Generalized Aggregation Operator [PDF]

International Journal of Computational Intelligence Systems, 2014
With respect to multiple attribute decision making (MADM) problems in which the attribute value takes the form of intuitionistic trapezoidal fuzzy number, a new decision making analysis method is developed.
Peide Liu, Ying Liu
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

T-Spherical Fuzzy Power Muirhead Mean Operator Based on Novel Operational Laws and Their Application in Multi-Attribute Group Decision Making

IEEE Access, 2019
T-spherical fuzzy set (T-SPFS) is a generalization of several fuzzy concepts such as fuzzy set (FS), intuitionistic FS, picture FS, Pythagorean FS, and q-rung orthopair FS.
Peide Liu, Qaisar Khan, Tahir Mahmood, Nasruddin Hassan   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

iAggregator: Multidimensional Relevance Aggregation Based on a Fuzzy Operator [PDF]

, 2014
International audienceRecently, an increasing number of information retrieval studies have triggered a resurgence of interest in redefining the algorithmic estimation of relevance, which implies a shift from topical to multidimensional relevance ...
Moulahi, Bilel, Ben Yahia, Sadok, Lynda Tamine, Tamine, Lynda, Sadok Ben Yahia, Bilel Moulahi   +5 more
core   +1 more source