Results 91 to 100 of about 135,667 (297)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Aggregation Functions Considering Criteria Interrelationships in Fuzzy Multi-Criteria Decision Making: State-of-the-Art

open access: yesIEEE Access, 2018
Aggregation function is an important component in an information aggregation or information fusion system. Interrelationships usually exist between the input arguments (e.g., the criteria in the multi-criteria decision making) of an aggregation function.
Le Sun, Hai Dong, Alex X. Liu
doaj   +1 more source

Aggregation on bipolar scales [PDF]

open access: yes
The paper addresses the problem of extending aggregation operators typically defined on $[0,1]$ to the symmetric interval $[-1,1]$, where the ``0'' value plays a particular role (neutral value).
Michel Grabisch
core  

A View of Averaging Aggregation Operators

open access: yesIEEE Transactions on Fuzzy Systems, 2007
This work was supported in part by Generalitat de Catalunya (AGAUR, 2004XT 00004) and by the Spanish MEC (projects CONSOLIDER INGENIO 2010 CSD2007-00004 and e-AEGIS TSI2007-65406-C03-02).
Vicenç Torra, Yasuo Narukawa
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Dual hesitant pythagorean fuzzy Hamacher aggregation operators in multiple attribute decision making

open access: yesArchives of Control Sciences, 2017
In this paper, we investigate the multiple attribute decision making (MADM) problem based on the Hamacher aggregation operators with dual Pythagorean hesitant fuzzy information.
Wei Guiwu, Lu Mao
doaj   +1 more source

Межканальная агрегация гиперспектральных изображений [PDF]

open access: yes, 2015
В данной статье предлагается алгоритм объединения каналов гиперспектрального изображения с помощью агрегационных операторов. В качестве таких операторов используются среднее арифметическое, среднее геометрическое, минимум и максимум, а также медиана ...
Martyanova, A. V.   +1 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Fuzzy modelling using a simplified rule base [PDF]

open access: yes, 2004
Transparency and complexity are two major concerns of fuzzy rule-based systems. To improve accuracy and precision of the outputs, we need to increase the partitioning of the input space.
Fung, C.C., Khan, M.S., Khor, S.W.
core   +1 more source

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