Results 81 to 90 of about 1,560,028 (331)

Amphiphilic Porphyrin Aggregates: A DFT Investigation

open access: yesMolecules, 2019
Owing to the attractive potential applications of porphyrin assemblies in photocatalysis, sensors, and material science, studies presently concerning porphyrin aggregation are widely diffused.
Federica Sabuzi   +4 more
doaj   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

The Greatest Common Decision Maker: A Novel Conflict and Consensus Analysis Compared with Other Voting Procedures

open access: yesMathematics, 2022
Consensus or conflict agreements, and how these change over time, have significant consequences for understanding the network behavior of human beings, especially when it is necessary to have agreements to move companies and countries forward peacefully.
Pedro García-del-Valle-y-Durán   +2 more
doaj   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

Computational study of aggregation mechanism in human lysozyme[D67H]. [PDF]

open access: yesPLoS ONE, 2017
Aggregation of proteins is an undesired phenomena that affects both human health and bioengineered products such as therapeutic proteins. Finding preventative measures could be facilitated by a molecular-level understanding of dimer formation, which is ...
Dharmeshkumar Patel, Serdar Kuyucak
doaj   +1 more source

Blow-up versus global existence of solutions to aggregation equations [PDF]

open access: yesarXiv, 2010
A class of nonlinear viscous transport equations describing aggregation phenomena in biology is considered. Optimal conditions on an interaction potential are obtained which lead either to the existence or to the nonexistence of global-in-time solutions.
arxiv  

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

Characterizing the Solvent‐Induced Inversion of Colloidal Aggregation During Electrophoretic Deposition

open access: yesAdvanced Materials Interfaces, 2023
Electrophoretic deposition (EPD) of colloidal particles is a practical system for the study of crystallization and related physical phenomena. The aggregation is driven by the electroosmotic flow fields and induced dipole moments generated by the ...
Justin R. DeMoulpied   +5 more
doaj   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Development of the Theory of Six Value Aggregation Paths in Network Modeling for Spatial Analyses

open access: yesISPRS International Journal of Geo-Information, 2020
The dynamic development of spatial structures entails looking for new methods of spatial analysis. The aim of this article is to develop a new theory of space modeling of network structures according to six value aggregation paths: minimum and maximum ...
Anna Maria Kowalczyk, Tomasz Bajerowski
doaj   +1 more source

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