Results 81 to 90 of about 266,965 (294)

Probing Globular Protein Self-Assembling Dynamics by Heterodyne Transient Grating Experiments

open access: yesApplied Sciences, 2019
In this work, we studied the propagation of ultrasonic waves of lysozyme solutions characterized by different degrees of aggregation and networking. The experimental investigation was performed by means of the transient grating (TG) spectroscopy as a ...
Sara Catalini   +4 more
doaj   +1 more source

Elements of a Theory of Simulation

open access: yes, 1995
Unlike computation or the numerical analysis of differential equations, simulation does not have a well established conceptual and mathematical foundation. Simulation is an arguable unique union of modeling and computation.
Barrett, Christopher, Rasmussen, Steen
core   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Red’s cafè

open access: yesAnd, 2020
The ability of physical places to become symbols of sociality and aggregation, belongs to that world of phenomena indefinable by the human sciences, far from any rational theory and made up of uncontrolled variables.
Andrea Parisella, Stefano Di Base
doaj  

Kosmotropes and chaotropes: modelling preferential exclusion, binding and aggregate stability [PDF]

open access: yes, 2004
Kosmotropic cosolvents added to an aqueous solution promote the aggregation of hydrophobic solute particles, while chaotropic cosolvents act to destabilise such aggregates. We discuss the mechanism for these phenomena within an adapted version of the two-
Moelbert, Susanne   +2 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Application of single-molecule analysis to singularity phenomenon of cells

open access: yesBiophysics and Physicobiology
Single-molecule imaging in living cells is an effective tool for elucidating the mechanisms of cellular phenomena at the molecular level. However, the analysis was not designed for throughput and requires high expertise, preventing it from reaching large
Michio Hiroshima   +3 more
doaj   +1 more source

Synthesis and Characterization of Multilayer 3D Chiral Polymers with Enhanced Optical Properties

open access: yesMolecules
This study reports the synthesis of novel multilayer 3D chiral polymers using 2,2′-(2,7-Naphthalenediyl)bis[4,4,5,5-tetramethyl-1,3,2-dioxaborolane] and 1,8-dibronaphthalene along with its derivatives as key precursors. Comprehensive characterization was
Sai Zhang   +9 more
doaj   +1 more source

Kinetics of self-induced aggregation in Brownian particles

open access: yes, 2007
We study a model of interacting random walkers that proposes a simple mechanism for the emergence of cooperation in group of individuals. Each individual, represented by a Brownian particle, experiences an interaction produced by the local unbalance in ...
Cecconi, Fabio   +2 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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