Results 41 to 50 of about 270,728 (294)

Modeling instrumental aggression in adults in a laboratory setting [PDF]

, 1978
Mummendey HD. Modeling instrumental aggression in adults in a laboratory setting. Psychological Research. 1978;40(2):189-193.Five experiments with 353 young adults performing a game on an aggression machine are reported, three of them testing hypotheses ...
Mummendey, Hans D.
core   +1 more source

Stimulating the ventrolateral prefrontal cortex (VLPFC) modulates frustration-induced aggression: A tDCS experiment

Brain Stimulation, 2020
Background: The prefrontal cortex is crucial for top-down regulation of aggression, but the neural underpinnings of aggression are still poorly understood.
Alessia Gallucci, Paolo Riva, Leonor J. Romero Lauro, Brad J. Bushman   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Prevalence of aggression and associated factors among inpatients with mental illness at tertiary hospitals in Southwestern Uganda

BMC Psychiatry
Background In mental health treatment facilities around the world, aggression aimed towards medical personnel and other patients is a serious issue. Types of aggression include; verbal aggression, aggression towards property, self-harm/auto-aggression ...
Badru Kayongo, Godfrey Zari Rukundo, Alain Favina, Samuel Maling   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Women, anger, and aggression an interpretative phenomenological analysis [PDF]

, 2008
This study reports a qualitative phenomenological investigation of anger and anger-related aggression in the context of the lives of individual women. Semistructured interviews with five women are analyzed using interpretative phenomenological analysis ...
Rachel Shaw, Jonathan A. Smith, Eatough, Virginia, Smith, Jonathan A., Shaw, R., Shaw, Rachel L., Virginia Eatough   +6 more
core   +1 more source

Persistence of aggression into adulthood in detained adolescent females

Comprehensive Psychiatry, 2014
Objective: Although detained adolescent females show high rates of severe aggression, we know little about the long-term impact of this risk-behavior. Furthermore, qualitative differences in aggression between males and females argue for gender specific ...
Anne A. Krabbendam, Lucres M.C. Jansen, Peter M. van de Ven, Elsa van der Molen, Theo A.H. Doreleijers, Robert R.J.M. Vermeiren   +5 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

A Conceptual Review of Lab-Based Aggression Paradigms

Collabra: Psychology, 2018
Aggression is often defined as a behavior that is done with the intent to harm an individual who is believed to want avoid being harmed (e.g., Baron & Richardson, 1994).
Randy J. McCarthy, Malte Elson
doaj   +1 more source