Results 61 to 70 of about 270,728 (294)

Predicting factors associated with aggression behavior among university students: a cross sectional study

open access: yesScientific Reports
Currently, there has been an alarming rise in aggression among university students. This study aimed to assess the prevalence of aggression among Palestinian university students and its association with depression and anxiety.
Muna Ahmead, Nuha El Sharif
doaj   +1 more source

Distinct psychological mechanisms for explicit and implicit aggression: evidence from the narcissism and sense of power

open access: yesFrontiers in Psychology
IntroductionAggression has been demonstrated a distinction between explicit and implicit social cognition. Explicit aggression refers to the conscious tendency to display aggressive behavior while maintaining necessary self-control.
Qi Hu   +6 more
doaj   +1 more source

The Relation of Violent Video Games to Adolescent Aggression: An Examination of Moderated Mediation Effect

open access: yesFrontiers in Psychology, 2019
To assess the moderated mediation effect of normative beliefs about aggression and family environment on exposure to violent video games and adolescent aggression, the subjects self-reported their exposure to violent video games, family environment ...
Rong Shao, Rong Shao, Yunqiang Wang
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Differential Effects of Neonatal Testosterone Treatment on Aggression in Two Selection Lines of Mice [PDF]

open access: yes, 1992
Selection lines of mice, artificially selected for aggression based upon the attack latency score (ALS), were used. In order to determine the relative contribution of neonatal testosterone (T) in the development of aggression, we vary the plasma-T level ...
Compaan, Josje C.,   +11 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Understanding associations between exhibited aggression and aggression seen on television and in video games in children with behavioural and emotional difficulties, attending specialist outpatient mental health services [PDF]

open access: yes
The possibility that seeing aggression on television and in video games might cause aggression in children is a public health concern. A systematic review found insufficient, contradictory and methodologically flawed evidence regarding this ...
Mitrofan, O.
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Effect of naloxone on food competition aggression in food-restricted high and low aggression pigeons (Columba livia)

open access: yesBrazilian Journal of Medical and Biological Research, 2004
We determined the effect of the opiate receptor antagonist naloxone on aggression, emotion, feeder control, and eating behavior in high and low aggression female pigeons maintained at 80% of their normal weight and exposed to food competition ...
C. Fachinelli   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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