Results 71 to 80 of about 716,714 (305)

Affect and the computer game player: the effect of gender, personality, and game reinforcement structure on affective responses to computer game-play [PDF]

, 2006
Previous research on computer games has tended to concentrate on their more negative effects (e.g., addiction, increased aggression). This study departs from the traditional clinical and social learning explanations for these behavioral phenomena and ...
Chumbley, J, Griffiths, MD
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Are all types of empathy associated with lower aggression in athletes? A cross-sectional study on Iranian athletes

BMC Psychology, 2022
Background This study aimed to evaluate the association between cognitive and affective empathy and aggression in a sample of Iranian athletes. Methods We designed a cross-sectional study.
Elham Mahmoudi, Amin Nakhostin-Ansari, Maryam Ranjbar, Amir Hossein Memari   +3 more
doaj   +1 more source

Isolation and social instigation in animal models of aggression: effects of an mGLU1 receptor antagonist administration [PDF]

, 2017
Isolate-induced aggression in male mice is a model widely used in psychoparmacology of aggression. Animals are usually isolated for 30 days and subsequently treated and confronted with an anosmic opponent in a neutral area.
Martin-Lopez, Maria Mercedes
core  

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Distinct psychological mechanisms for explicit and implicit aggression: evidence from the narcissism and sense of power

Frontiers in Psychology
IntroductionAggression has been demonstrated a distinction between explicit and implicit social cognition. Explicit aggression refers to the conscious tendency to display aggressive behavior while maintaining necessary self-control.
Qi Hu, Zijun Meng, Jiantao Lu, Yu Zhu, Yu Zhu, Kaihua Zhang, Qian Zhang   +6 more
doaj   +1 more source

Pervasive, hard-wired and male: Qualitative study of how UK adolescents view alcohol-related aggression.

PLoS ONE, 2018
Laboratory studies of alcohol-inexperienced adolescents show that aggression can be primed by alcohol-related stimuli, suggesting that alcohol-related aggression is partly socially learned. Script theory proposes that alcohol-related aggression 'scripts'
Lydia Whitaker, Stephen L Brown, Bridget Young, Richard Fereday, Sarah M Coyne, Pamela Qualter   +5 more
doaj   +1 more source