Results 151 to 160 of about 12,311,713 (381)

Aging in Japan [PDF]

, 2000
In this paper, Dr. Ibe addresses some of the problems confronting Japan today, among them pensions, long-term care, housing policies and the legal system.
Hideo Ibe
core  

Aging, Frailty, and the Microbiome—How Dysbiosis Influences Human Aging and Disease

, 2020
John P. Haran, Beth A. McCormick
openalex   +2 more sources

Systemic clearance of p16^INK4a‐positive senescent cells mitigates age‐associated intervertebral disc degeneration [PDF]

, 2019
Prashanti Patil, Qing Dong, Dong Wang, Jianhui Chang, Christopher D. Wiley, Marco Demaria, Joon Lee, James D. Kang, Laura J. Niedernhofer, Paul D. Robbins, Gwendolyn Sowa, Judith Campisi, Daohong Zhou, Nam Vo   +13 more
openalex   +1 more source

Aging shifts mitochondrial dynamics toward fission to promote germline stem cell loss [PDF]

, 2020
Oyundari Amartuvshin, Chi‐Hung Lin, Shao‐Chun Hsu, Shih‐Han Kao, Alvin Chen, Wei‐Chun Tang, Hsin-Hung Chou, Dong‐Lin Chang, Yen‐Yang Hsu, Bai‐Shiou Hsiao, Elham Rastegari, Kun‐Yang Lin, Yuting Wang, Chi‐Kuang Yao, Guang‐Chao Chen, Bi‐Chang Chen, Hwei‐Jan Hsu   +16 more
openalex   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Aging and diet alter the protein ubiquitylation landscape in the mouse brain

Nature Communications
Post-translational modifications (PTMs) regulate protein homeostasis, but how aging impacts PTMs remains unclear. Here, we used mass spectrometry to reveal changes in hundreds of protein ubiquitylation, acetylation, and phosphorylation sites in the mouse
Antonio Marino, Domenico Di Fraia, Diana Panfilova, Amit Kumar Sahu, Alberto Minetti, Omid Omrani, Emilio Cirri, Alessandro Ori   +7 more
doaj   +1 more source

Slowing Down: Age-Related Neurobiological Predictors of Processing Speed [PDF]

, 2011
Mark A. Eckert
openalex   +1 more source

Social Isolation and Loneliness during COVID-19 Lockdown: Associations with Depressive Symptoms in the German Old-Age Population

, 2021
Felix Müller, Susanne Röhr, Ulrich Reininghaus, Steffi G. Riedel‐Heller   +3 more
openalex   +1 more source

Ageing [PDF]

Nature, 2010
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source