Results 201 to 210 of about 12,311,713 (381)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Mitochondria, Oxidants, and Aging

Cell, 2005
R. Balaban, S. Nemoto, T. Finkel
semanticscholar   +1 more source

From Iberia to the Southern Levant: The Movement of Silver Across the Mediterranean in the Early Iron Age [PDF]

, 2019
Jonathan R. Wood, Ignacio Montero Ruíz, Marcos Martinón‐Torres   +2 more
openalex   +1 more source

1,25-Dihydroxyvitamin D Deficiency Accelerates Aging-related Osteoarthritis via Downregulation of Sirt1 in Mice [PDF]

, 2023
Jie Chen, Jiao Zhang, Jie Li, Ran Qin, Na Lü, David Goltzman, Dengshun Miao, Renlei Yang   +7 more
openalex   +1 more source

Aging

Experimental Animals, 2021
openaire   +3 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Incidence of viral respiratory infections in a prospective cohort of outpatient and hospitalized children aged ≤5 years and its associated cost in Buenos Aires, Argentina [PDF]

, 2015
Débora Natalia Marcone, Lizette O. Durand, Eduardo Azziz‐Baumgartner, Santiago Vidaurreta, Jorge Ekstrom, Guadalupe Carballal, Marcela Echavarría   +6 more
openalex   +1 more source

Quality-of-Life Evaluation among the Oldest-Old in China under the “Active Aging Framework” [PDF]

, 2022
Xin Xu, Yuan Zhao, Jianfang Zhou, Siyou Xia   +3 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Towards precise ages and masses of Free Floating Planetary Mass Brown Dwarfs [PDF]

, 2013
J. Canty, P. W. Lucas, P. F. Roche, D. J. Pinfield   +3 more
openalex   +1 more source