Results 41 to 50 of about 1,517,822 (306)

Tau oligomers modulate synapse fate by eliciting progressive bipartite synapse dysregulation and synapse loss

Molecular Neurodegeneration
Background Synapse function is critical for cognition, and synapse loss is highly correlated with cognitive decline in Alzheimer’s disease and related dementias.
Kristeen A. Pareja-Navarro, Christina D. King, Grant Kauwe, Yani Y. Ngwala, Doyle Lokitiyakul, Ivy Wong, Aaryan Vira, Yaofu Liu, Jackson H. Chen, Mahima Sharma, Gabriel Navarro, Olfat Malak, Chuankai Zhou, Birgit Schilling, Tara E. Tracy   +14 more
doaj   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

[Coalition for Aging LGBT Initial Board Exploratory Meeting Document] [PDF]

, 2015
Initial Board Exploratory Meeting documents from the Coalition for Aging LGBT Records (The Dallas Way)
Coalition for Aging LGBT
core  

Characterization of an in vitro 3D intestinal organoid model by using massive RNAseq-based transcriptome profiling

Scientific Reports, 2021
Organoids culture provides unique opportunities to study human diseases and to complement animal models. Several organs and tissues can be in vitro cultured in 3D structures resembling in vivo tissue organization.
Jing Lu, Anna Krepelova, Seyed Mohammad Mahdi Rasa, Francesco Annunziata, Olena Husak, Lisa Adam, Suneetha Nunna, Francesco Neri   +7 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

[Coalition for Aging LGBT Board of Directors Meeting Agenda] [PDF]

, 2015
Board of Directors Meeting agenda document from the Coalition for Aging LGBT Records (The Dallas Way)
Coalition for Aging LGBT
core  

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source

Be the voice. Take action. Tigether [PDF]

, 2012
Jan. 12, 2012-; "... A blog-like publication that connects interest Ohioans to news and information about issues affecting older Ohioans and the people who care for and serve them."; Not published Feb.-Nov. 2013.; Issue for Jan.
Western Reserve Area Agency on Aging, Perkins, Fatima   +1 more
core  

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

Improved Early Referral in Long‐Term Survivor Care With Institutional Standardized Practice Among Childhood Leukemia Survivors#

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In 2018, the Texas Children's Cancer and Hematology Center Leukemia Program implemented a practice standard to support the transition from treatment to survivorship that includes shared, alternating care between leukemia and survivorship clinicians and a reminder to refer survivors to the long‐term survivor clinic (LTSC) 2 years after ...
Ji Yun Tark, Kayla L. Foster, Omar Shakeel, Mary C. Shapiro, Shawki L. Qasim, ZoAnn Dreyer, Eric S. Schafer, Ashley M. Butler, Austin L. Brown, Maria Monica Gramatges   +9 more
wiley   +1 more source