Results 51 to 60 of about 2,198,545 (274)
Journal of Diabetes ResearchThis review is aimed at unraveling the intricacies of diabetic self-management among geriatric people, drawing on current insights and understanding the complex paths geriatric people navigate.
David F. Lo +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Epigenetics, 2020 Metabolic syndrome (MetS) is a cluster of cardiometabolic risk factors for all-cause mortality, cardiovascular disease, and cancer. Identifying epigenetic alterations associated with MetS in African Americans (AAs) and Whites may provide insight into ...
Kumaraswamy Naidu Chitrala +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
UVA: A Universal Variational Framework for Continuous Age Analysis [PDF]
arXiv, 2019 Conventional methods for facial age analysis tend to utilize accurate age labels in a supervised way. However, existing age datasets lies in a limited range of ages, leading to a long-tailed distribution. To alleviate the problem, this paper proposes a Universal Variational Aging (UVA) framework to formulate facial age priors in a disentangling manner.
arxiv
A method to estimate stellar ages from kinematical data [PDF]
, 2018 We present a method to build a probability density function (pdf) for the age of a star based on its peculiar velocities $U$, $V$ and $W$ and its orbital eccentricity. The sample used in this work comes from the Geneva-Copenhagen Survey (GCS) which contains both the spatial velocities, orbital eccentricities and isochronal ages for about $14\,000 ...
arxiv +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Nature Communications, 2019 Notch signaling mediates intestinal enteroblast specification in Drosophila but the molecular mechanism as to how this is regulated is unclear. Here, the authors show that the transcription factor Klumpfuss ensures enteroblast commitment through ...
Jerome Korzelius +9 more
doaj +1 more source
Red Blood Cell Oxidative Stress impairs oxygen delivery and induces Red Blood Cell Aging
Frontiers in Physiology, 2014 Red Blood Cells (RBCs) need to deform and squeeze through narrow capillaries. Thus, decreased deformability of RBCs contributes to the elimination of aged or damaged RBCs from the circulation.
Joy eMohanty +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source