Results 61 to 70 of about 2,198,545 (274)
Journal of Cachexia, Sarcopenia and MuscleBackground Handelin is a bioactive compound from Chrysanthemum indicum L. that improves motor function and muscle integrity during aging in Caenorhabditis elegans.
Hui‐Jie Zhang +11 more
doaj +1 more source
Physiology and pathology of calcium signaling in the brain
Frontiers in Pharmacology, 2012 Calcium (Ca2+) plays fundamental and diversified roles in neuronal plasticity. As second messenger of many signaling pathways, Ca2+ as been shown to regulate neuronal gene expression, energy production, membrane excitability, synaptogenesis, synaptic ...
Elisa Mitikp Kawamoto +2 more
doaj +1 more source
arXiv, 2014 A groupoid G is called an AG-groupoid if it satisfies the left invertive law: (ab)c = (cb)a. An AG-group G, is an AG-groupoid with left identity e \in G (that is, ea = a for all a \in G) and for all a \in G there exists a' \in G such that a.a' = a'.a = e.
arxiv
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source
Single Molecule Analysis of Laser Localized Interstrand Crosslinks
Frontiers in Genetics, 2016 DNA interstrand crosslinks (ICLs) block unwinding of the double helix, and have always been regarded as major challenges to replication and transcription. Compounds that form these lesions are very toxic and are frequently used in cancer chemotherapy. We
Jing eHuang +6 more
doaj +1 more source
Improved Age Estimation for Solar-Type Dwarfs Using Activity-Rotation Diagnostics [PDF]
, 2008 While the strong anti-correlation between chromospheric activity and age has led to the common use of the Ca II H & K emission index (R'_HK = L_HK/L_bol) as an empirical age estimator for solar type dwarfs, existing activity-age relations produce implausible ages at both high and low activity levels.
arxiv +1 more source
Molecular Oncology, EarlyView.This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke +12 more
wiley +1 more source
Longitudinal Face Modeling via Temporal Deep Restricted Boltzmann Machines [PDF]
, 2016 Modeling the face aging process is a challenging task due to large and non-linear variations present in different stages of face development. This paper presents a deep model approach for face age progression that can efficiently capture the non-linear aging process and automatically synthesize a series of age-progressed faces in various age ranges. In
arxiv +1 more source
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
Personalized Age Progression with Aging Dictionary [PDF]
arXiv, 2015 In this paper, we aim to automatically render aging faces in a personalized way. Basically, a set of age-group specific dictionaries are learned, where the dictionary bases corresponding to the same index yet from different dictionaries form a particular aging process pattern cross different age groups, and a linear combination of these patterns ...
arxiv