Results 141 to 150 of about 981,146 (304)

Implementation of Fuzzy Logic Scheme for Assessment of Power Transformer Oil Deterioration Using Imprecise Information

Energies
This research aims to analyze the implementation of a fuzzy logic-based approach in improving the diagnosis of power transformer oil deterioration, which is critical for maintaining the efficient performance and operational life of transformers ...
Zuhaib Nishter, Fangzong Wang
doaj   +1 more source

Molecular Simulation Study on the Aging Mechanism of NEPE Propellant Matrix. [PDF]

Molecules, 2023
Kong L, Dong K, Tang Y, Yang C, Xiao Y.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Study on Aging Mechanism and High-Temperature Rheological Properties of Low-Grade Hard Asphalt. [PDF]

Materials (Basel), 2023
Song L, Xie X, Tu P, Fan J, Gao J.
europepmc   +1 more source

Microstructure and mechanical properties of bulk yttria-partially-stabilized zirconia [PDF]

A commercially available bulk 4.5 mole percent yttria-(Y2O3) partially stabilized zirconia (PSZ) was studied by light microscopy, X-ray analysis, microhardness measurement, and fracture toughness testing.
Maier, R. D., Mitchell, T. E., Valentine, P. G.   +2 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Anti-aging mechanism of different age donor-matched adipose-derived stem cells. [PDF]

Stem Cell Res Ther, 2023
Wang T, Li Y, Zhu Y, Liu Z, Huang L, Zhao H, Zhou Z, Wu Q.   +7 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Aging Analysis of Semiconductive Silicone Rubber for 10 kV Cold-Shrink Cable Accessories

Energies
This study focuses on the semiconductive silicone rubber of 10 kV cold-shrink accessories. Accelerated thermal aging tests were conducted on the semiconductive silicone rubber, obtaining tensile stress–strain curves at various time points after thermal ...
Jun Yu, Zhijian Zhang, Weifeng Ren, Dongxing Yang, Dian Wu, Zhiqiang Ning, Chunhua Fang, Junxiong Wu   +7 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source