Results 61 to 70 of about 981,146 (304)
Biological mechanisms of ageing [PDF]
Eye, 1987 In a short review of the theories or proposed biological mechanisms of ageing it is necessary to be very selective in the ideas which are included or rejected. Although many theories of ageing are advanced in the literature a high proportion can be considered to be special cases of a previous hypothesis. No one individual theory satisfactorily explains
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Molecular mechanisms of erythrocyte aging [PDF]
Biological Chemistry, 2015 Abstract Anemia and hemorrhagic shock are leading causes of morbidity and mortality worldwide, and transfusion of human blood products is the ideal treatment for these conditions. As human erythrocytes age during storage in blood banks they undergo many biochemical and structural changes, termed the red blood cell ‘storage lesion’.
Richard S, Hoehn +4 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack +39 more
wiley +1 more source
Long-term calorie restriction in humans is not associated with indices of delayed immunologic aging: A descriptive study. [PDF]
, 2017 BACKGROUND: Delayed immunologic aging is purported to be a major mechanism through which calorie restriction (CR) exerts its anti-aging effects in non-human species.
Epel, Elissa S +8 more
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Data-Driven Battery Aging Mechanism Analysis and Degradation Pathway Prediction
Batteries, 2023 Capacity decline is the focus of traditional battery health estimation as it is a significant external manifestation of battery aging. However, it is difficult to depict the internal aging information in depth.
Ruilong Xu, Yujie Wang, Zonghai Chen
doaj +1 more source
Age-related deterioration of rod vision in mice [PDF]
, 2010 Even in healthy individuals, aging leads to deterioration in visual acuity, contrast sensitivity, visual field, and dark adaptation. Little is known about the neural mechanisms that drive the age-related changes of the retina and, more specifically ...
Crouch, Rosalie K +3 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Age Effects on Hypocotyl Mechanics
PLOS ONE, 2016 Numerous studies deal with composition and molecular processes involved in primary cell wall formation and alteration in Arabidopsis. However, it still remains difficult to assess the relation between physiological properties and mechanical function at the cell wall level.
Friederike Saxe +7 more
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Cellular ageing mechanisms in osteoarthritis [PDF]
Mammalian Genome, 2016 Age is the strongest independent risk factor for the development of osteoarthritis (OA) and for many years this was assumed to be due to repetitive microtrauma of the joint surface over time, the so-called 'wear and tear' arthritis. As our understanding of OA pathogenesis has become more refined, it has changed our appreciation of the role of ageing on
Sacitharan, P, Vincent, A
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