Results 71 to 80 of about 981,146 (304)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Analysis the Aging Mechanism of Qu Chenpi Based on Widely-targeted Metabolomics

open access: yesShipin gongye ke-ji
Objective: To analyze the differential metabolites of Qu Chenpi, and to provide the scientific basis for the aging mechanism, development, and utilization of Qu Chenpi.
Jiajun WANG   +8 more
doaj   +1 more source

Effect of thermo-oxidative aging on mechanical properties and tribological behaviors of acrylonitrile-butadiene rubber

open access: yesCailiao gongcheng, 2021
Acrylonitrile-butadiene rubber (NBR) was conducted with accelerated aging under the thermo-oxidative environment, a test on the tribological performance of aged NBR was carried out using UMT-3 tribo-tester.
LI Bo   +5 more
doaj   +1 more source

Aging mechanism in tunable Pickering emulsion

open access: yes, 2015
We study the stability of a model Pickering emulsion system. A special counter-flow microfluidics set-up was used to prepare monodisperse Pickering emulsions, with oil droplets in water.
Daillant, J.   +3 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Aging mechanisms in bone

open access: yesBoneKEy Reports, 2012
Advancing age and loss of bone mass and strength are closely linked. Elevated osteoblast and osteocyte apoptosis and decreased osteoblast number characterize the age-related skeletal changes in humans and rodents. Similar to other tissues, oxidative stress increases in bone with age.
openaire   +3 more sources

Aging and asthma: pathophysiological mechanisms [PDF]

open access: yesAllergy, 2003
Non ...
Vignola, A.   +4 more
openaire   +4 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Total hip arthroplasty, through the direct anterior approach, for a femoral neck fracture of ipsilateral transfemoral amputee: a case report

open access: yesFrontiers in Surgery
ObjectiveFemoral neck fractures in transfemoral amputees are rare, and their management remains controversial, particularly in individuals with short residual limb lengths. Traditional approaches to total hip arthroplasty (THA), such as the anterolateral,
Xiangde Zhao   +6 more
doaj   +1 more source

Mechanism and kinetics of aging in Inconel 718 [PDF]

open access: yes, 1970
Age hardening in Inconel 718 is investigated using Brinell hardness measurements.
Hensley, W. E.   +2 more
core   +1 more source

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