Results 131 to 140 of about 290,636 (313)

Bonding Durability Evaluation of Polymer-Modified Emulsified Asphalt Microsurfacing

Advances in Materials Science and Engineering
At present, there are few research studies on the durability of microsurfacing. To further improve the service quality and durability of microsurfacing, five kinds of polymer-modified emulsified asphalt were used to prepare microsurfacing mixture.
Hao Fu, Qian Chen, Xiaolong Sun, Wenwu Zhang, Shanshan Wang   +4 more
doaj   +1 more source

Relationship of Ageing to Insulin Resistance and Atherosclerosis

Metabolites
Ageing drives a vicious cycle of insulin resistance (IR) and atherosclerosis through shared pathological pathways. This review aims to synthesise the current understanding of the molecular mechanisms that connect ageing, IR, and atherosclerosis, with a particular focus on oxidative stress, chronic inflammation, and metabolic disturbances.
Xiaoyu Hao, Siying Tu, Da Pan, Wang Liao, Ligang Yang, Shaokang Wang, Guiju Sun   +6 more
openaire   +2 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Enhancing the Mechanical Properties and Aging Resistance of 3D-Printed Polyurethane through Polydopamine and Graphene Coating. [PDF]

Polymers (Basel), 2023
Tung CC, Lin YH, Chen YW, Wang FM.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

The effects of aging, exercise and food restriction on the development of insulin resistance in adipocytes of young rats

, 1987
Male Sprague-Dawley rats were used to determine whether insulin resistance develops between 1.5-4.0 months of age and whether it is related to aging or the development of obesity.
Kastello, Gary M.
core  

Laboratory Investigation of Storage Stability and Aging Resistance of Slightly SBS-Modified Bitumen Binders. [PDF]

Materials (Basel), 2023
Yu H, Mo L, Zhang Y, Qi C, Wang Y, Li X.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Effects of resistance training and detraining on muscle strength and blood lipid profiles in postmenopausal women

, 2002
Objectives: To study the effects of eight weeks of supervised, low intensity resistance training (80% of 10 repetition maximum (10RM)) and eight weeks of detraining on muscle strength and blood lipid profiles in healthy, sedentary postmenopausal women.
Cable, N T, Sale, C, Elliott, KJ, Elliott, K.J., Cable, N.T., Cable, NT, Sale, C., Elliott, K J   +7 more
core   +1 more source

Enhanced creep resistance in Mg-Y-Nd alloy via regulating prior thermo-mechanical treatment

Journal of Magnesium and Alloys
In this study, the tensile creep behavior of a hot-rolled Mg-4Y-3.5Nd alloy subjected to different prior thermo-mechanical treatments was investigated at 220 ℃.
Zhirou Zhang, Qinghuan Huo, Yuxiu Zhang, Gantao Zhao, Hiromi Nagaumi, Xuyue Yang   +5 more
doaj   +1 more source