Results 41 to 50 of about 2,734,594 (261)

Elevated mutagenesis does not explain the increased frequency of antibiotic resistant mutants in starved aging colonies. [PDF]

open access: yesPLoS Genetics, 2013
The frequency of mutants resistant to the antibiotic rifampicin has been shown to increase in aging (starved), compared to young colonies of Escherichia coli.
Sophia Katz, Ruth Hershberg
doaj   +1 more source

Aging process and strengthening mechanism of Cu–Cr–Ni alloy with superior stress relaxation resistance

open access: yesJournal of Materials Research and Technology, 2022
With the development trend of connectors to high-current and high-temperature service, copper alloy connectors are required to have superior stress relaxation resistance.
Guojie Wang   +7 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

Enhanced Ozone Aging Resistance of Natural Rubber with 2-Mercaptobenzothiazole as the Constant-Viscosity Agent

open access: yesJournal of Chemistry, 2023
For the actual storage and serving, a phenomenon of hardening and cracking always occurs in the natural rubber (NR), which sharply reduces the mechanical performance and hinders the further application of NR.
Juan Zhou   +5 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Effect of aging on the low-temperature performance of fiber-reinforced asphalt mixtures

open access: yesAIP Advances, 2023
To study the effect of aging on the low-temperature crack resistance of fiber asphalt mixes, three kinds of fibers (lignin fiber, polyester fiber, and basalt fiber) were dry blended into AC-13 asphalt mixes to prepare unaged, asphalt aged (that is, the ...
Jinrong Wu, Yanyan Hu
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Aging effect in nasal resistance.

open access: yesNippon Jibiinkoka Gakkai Kaiho, 1984
5歳から84歳までの鼻疾患,呼吸器疾患のない男女501例について,一方向流によるpassive anterior法にて鼻腔抵抗の測定を行い,5歳から16歳までの各年齢および15歳以上の6つの年齢群ごとの測定値を示し,年齢と鼻腔抵抗の変化につき検討を加え,次のような結果を得た.1) 5歳から16歳までの抵抗の変化は,a) 8歳までの抵抗の高い時期,b) それに続き11歳頃までの比較的急激に抵抗が低下する時期,およびc) それ以後の抵抗の変動が認められる時期の3つに分けられる.a)においてはアデノイドの存在が,b)においては鼻腔の大きさの増大とアデノイドの消退が,c)においては鼻腔や鼻甲介の発育の不均衡と自律神経系の影響が考えられた.2) 20歳以後の抵抗の変化には次の2つの特徴がみられた.a ...
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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