Results 181 to 190 of about 694,962 (317)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Development of core outcome set for healthy aging treatment in primary care settings. [PDF]

Integr Med Res
Jang S, Jeong H, Park J, Ko MM, Jung J.
europepmc   +1 more source

Microstructure Evolution and Mechanical Properties of As-Cast and As-Compressed ZM6 Magnesium Alloys during the Two-Stage Aging Treatment Process. [PDF]

Materials (Basel), 2021
Fu J, Chen S.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

The Effect of Aging Treatment on the Corrosion Behavior of 17-4PH Stainless Steel. [PDF]

Materials (Basel)
Zhou C, Lv Y, Zhang L.
europepmc   +1 more source

Effects of Aging Treatment on Corrosion Behavior of a Tensile Deformed Al-Cu-Mn-Fe-Zr Alloy in 3.5% NaCl Solution. [PDF]

Materials (Basel), 2021
Tian Q, Yang QM, Lin YC, Wang JQ, Zhu XH.   +4 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

The Effect of Aging Treatment on the Properties of Cold-Rolled Cu-Ni-Si-Co Alloys with Different Mg Contents. [PDF]

Materials (Basel)
Wu D, Hu J, Hu Q, Wu L, Guan B, Zeng S, Xing Z, Wang J, Xu J, Huang G, Liu J.   +10 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Effects of Aging Treatment on the Microstructure and Mechanical Properties of Rene 41 Alloy and the Strengthening Mechanisms. [PDF]

Materials (Basel)
Zhang X, Han H, Tang P, Zhou Y, Xiao D, Fu J, Chen J, Feng S, Zhang J.   +8 more
europepmc   +1 more source