Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Effect of Si, Mn, Be and Sr Addition on the Tensile Properties of 6061 Type Alloys: Role of Aging Treatment. [PDF]
Materials (Basel), 2023 Samuel AM +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The Role of Mg Content and Aging Treatment on the Tensile and Fatigue Properties of Die-Cast 380 Alloy. [PDF]
Materials (Basel), 2022 Samuel AM +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Effect of Artificial Aging Treatment on the Mechanical Properties and Regulation of Precipitated Phase Particles of High-Pressure Die-Cast Thin-Wall AlSi10MnMg Longitudinal Carrier. [PDF]
Materials (Basel), 2023 Zhao X +5 more
europepmc +1 more source
Trap characterization in composite of solid-liquid using dual-level trap model and TSDC method
Charge trap is considered to be one of the effective characteristic parameters for qualitatively evaluating the aging status of insulating material.
Chen, George +4 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Effect of Aging Treatment on Microstructural Evolution and Mechanical Properties of the Electron Beam Cold Hearth Melting Ti-6Al-4V Alloy. [PDF]
Materials (Basel), 2022 Yu J +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source