Results 141 to 150 of about 1,451,454 (310)

Baby-Boom Aging and Average Living Standards [PDF]

A calibrated overlapping generations model is used to investigate the effect on living standards of the aging baby boom. The relative scarcity of labor when baby boomers are old raises the wage-rental ratio by an amount that is sufficient to ensure that ...
Malick Souare, William Scarth
core   +3 more sources

Effect of Aging Treatment on the Strength and Microstructure of 7075-Based Alloys Containing 2% Li and/or 0.12% Sc. [PDF]

Materials (Basel), 2023
Tahmasbi A, Samuel AM, Zedan Y, Songmene V, Samuel FH.   +4 more
europepmc   +1 more source

Transverse flexural tests as a tool for assessing damage to PMR-15 composites from isothermal aging in air at elevated temperatures [PDF]

To date, the effect of thermo-oxidative aging on unidirectional composite mechanical properties has been monitored by the measurement of interlaminar shear strength (ILSS) and either three or four point longitudinal flexural strength (LFS) of the ...
Bowles, Kenneth J.
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Effect of the Solid Solution and Aging Treatment on the Mechanical Properties and Microstructure of a Novel Al-Mg-Si Alloy. [PDF]

Materials (Basel), 2023
Chen Y, Wei W, Zhao Y, Shi W, Zhou X, Rong L, Wen S, Wu X, Gao K, Huang H, Nie Z.   +10 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

A Study on the Mechanical Behavior and Deformation Mechanism of the Aged Ni2CoCr0.5Si0.3Al0.1Ti0.1 Medium Entropy Alloy

Taiyuan Ligong Daxue xuebao
Purposes A novel type of Ni2CoCr0.5Si0.3Al0.1Ti0.1 medium entropy alloy is designed in this work. Methods Trace amounts of Si, Al, and Ti elements are added to the non-equiatomic ratio NiCoCr-based medium entropy alloy, and dispersed coherent L12 phase ...
LUO Shunhui, CHANG Hui, WANG Qiang, ZHANG Jiaxin, ZHANG Tuanwei, WANG Zhihua   +5 more
doaj   +1 more source

Effect of Aging Treatment on the Microstructure and Properties of 2.2 GPa Tungsten-Containing Maraging Steel. [PDF]

Materials (Basel), 2023
Han S, Li X, Liu Y, Geng R, Lei S, Li Y, Wang C.   +6 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Microplastic Categories Distinctively Impact Wastewater Bacterial Taxonomic Composition and Antimicrobial Resistance Genes

Microorganisms
Wastewater treatment plants (WWTPs) may serve as hotspots for pathogens and promote antimicrobial resistance (AMR). Plastic debris in wastewater could further contribute to AMR dissemination. The aim of this study was to investigate the impact of various
Tam Thanh Tran, Kabelo Stephans Stenger, Marte Strømmen, Cornelius Carlos Bezuidenhout, Odd-Gunnar Wikmark   +4 more
doaj   +1 more source