Results 131 to 140 of about 694,962 (317)

Nanoparticles-based anti-aging treatment of Alzheimer's disease. [PDF]

Drug Deliv, 2022
Chu JJ, Ji WB, Zhuang JH, Gong BF, Chen XH, Cheng WB, Liang WD, Li GR, Gao J, Yin Y, Yin Y.   +10 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Pharmacological and functional approaches for the treatment of brain aging

openIl brain aging, o invecchiamento cerebrale, è un complesso insieme di processi che si sviluppano con l'avanzare dell'età e comportano l'alterazione strutturale e funzionale del cervello.
D'AGOSTINO, ANDREA
core  

Economic Security in an Aging Canadian Population [PDF]

This paper has been written to bring up to date materials in a monograph that was a part of the Butterworths series of monographs in social gerontology, in particular, the 1991 monograph entitled: Economic Security in an Aging Population (Brown, 1991 ...
Robert L. Brown
core  

Chloroquine Causes Aging-like Changes in Diaphragm Neuromuscular Junction Morphology in Mice

Autophagy impairments have been implicated in various aging conditions. Previous studies in cervical motor neurons show an age-dependent increase in the key autophagy proteins LC3 and p62, reflecting autophagy impairment and autophagosome accumulation ...
Carlos B. Mantilla, Chloe I. Gulbronson, Sepideh Jahanian, Heather M. Gransee, Gary C. Sieck   +4 more
core   +1 more source

Hemodynamic Aging as the Consequence of Structural Changes Associated with Early Vascular Aging (EVA). [Elektronisk resurs]

, 2014
An increase in peripheral vascular resistance at rest is not routinely observed in healthy older persons, but often associated with increased stiffness of central elastic arteries, as hallmarks of aging effects on the vasculature, referred to as early ...
Nilsson, Peter,, Lund University.
core   +1 more source

Optimization of the Mechanical and Corrosion Resistance of Alloy 625 through Aging Treatments

Crystals
In the as-annealed condition, the nickel-based Alloy 625 has excellent mechanical and corrosion properties compared to those of common stainless steels.
Barbara Rivolta, Riccardo Gerosa, Davide Panzeri, Arsalan Nazim   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Essential Pieces of the Puzzle: The Roles of VEGF and Dopamine in Aging

Aging is a well-known, complex physiological process characterized by progressive functional decline and increased susceptibility to disease, particularly in the cardiovascular and nervous systems.
Sanjay P. Tirupattur, Melanie B. Thompson, Laxmansa C. Katwa, Nandini Vishwakarma   +3 more
core   +1 more source

Effect of Aging Treatment on the Strength and Microstructure of 7075-Based Alloys Containing 2% Li and/or 0.12% Sc. [PDF]

Materials (Basel), 2023
Tahmasbi A, Samuel AM, Zedan Y, Songmene V, Samuel FH.   +4 more
europepmc   +1 more source