Results 231 to 240 of about 583,540 (283)

Protection and Delivery of Phytochemicals from Passive Encapsulation to Guaranteed Self‐Assembly Induced by Amyloid Template for Chronic Disease Prevention via Modulating Microbial‐Host Crosstalk

Advanced Science, EarlyView.
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai, Siying Cheng, Fengguang Ma, Xiaorong Zhang, Jianan Huang, Zhonghua Liu, Bing Hu   +6 more
wiley   +1 more source

Promotion of DFU Wound Healing via BRG1–COL16A1 Axis in Fibroblasts

Advanced Science, EarlyView.
In normal wound healing, transcription factor BRG1 is upregulated and binds the COL16A1 promoter to enhance its expression, promoting fibroblast proliferation, migration, contraction, extracellular matrix deposition, and granulation tissue formation, thus accelerating wound closure.
Penghui Wang, Jiaming Sun, Ying Wang, Bichen Ren, Yuxin Liu, Yunhan Liu, Liang Chen, Lu Yu, Tao Dai, Li Yu, Zhihui Dong   +10 more
wiley   +1 more source

Neurobiological alteration in agitation in Alzheimer’s disease and possible interventions

Frontiers in Psychiatry
Jagadeesh S. Rao, María Alejandra Tangarife, Ram Mukunda   +2 more
doaj   +1 more source

The Association of Thyroid Function on Cognition and Neuropsychiatric Symptoms in Patients with Cognitive Impairment. [PDF]

Neuropsychiatr Dis Treat
Lin YR, Chang MC, Wang WF, Tung YC, Jhang KM.   +4 more
europepmc   +1 more source

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

Advanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao, Ruiqi Zhang, Rujun Wei, Huimin Fan, Yongfei Hu, Wenyu Shi, Jinfeng Wang   +6 more
wiley   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

The role of the endocannabinoid system in managing neuropsychiatric symptoms in Alzheimer's disease. [PDF]

Front Psychiatry
Rao JS, Alejandra Tangarife M, Venegas MM, Forero B, González Tamayo LL, Escobar-Gallego JP, Rodríguez-Soacha DA, Ferreiros A, Mukunda R.   +8 more
europepmc   +1 more source

Current evidence of randomized clinical trials on hospice-eligible patients with agitation and dementia: A narrative review. [PDF]

Palliat Support Care
Wang OY, Calev N, Mintzer J, Fritts A, Molina-Henry DP, Grill JD, Raman R.   +6 more
europepmc   +1 more source

Agitation in Alzheimer's disease: From assessment to therapeutics. [PDF]

World J Psychiatry
Teixeira AL, Kim Y, Cordeiro TM, de Erausquin GA, Rocha NP.   +4 more
europepmc   +1 more source

Identifying central behavioral and psychological symptoms associated with care time in older adults with dementia: a network analysis. [PDF]

Front Public Health
Liu C, Luo Q, Zhou Y, Li H, Liu H, Hu X.
europepmc   +1 more source