Results 41 to 50 of about 292,291 (303)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Naltrexone Induced Agitation Management: Employing a Hybrid Artificial Neural Network Model to Determine the Appropriate Dosage of Intravenous Diazepam

Namık Kemal Tıp Dergisi
Aim: Agitation is a prevalent symptom of opioid withdrawal caused by naltrexone. Managing agitation induced by naltrexone poses challenges as current drug interventions are either ineffective or require intensive care.
Seyed Ali MOHTARAMI, Sayed Masoud HOSSEINI, Shahin SHADNIA, Babak MOSTAFAZADEH, Peyman Erfan Talab EVINI, Omid MEHRPOUR, Shakiba FARHADPUR, Mitra RAHIMI   +7 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Prognostic significance of predictors of early postoperative cognitive disorders in patients after traumatic surgeries (prospective cohort study)

Вестник анестезиологии и реаниматологии
The objective was to determine the prognostic value of predictors of early postoperative cognitive disorders in traumatological patients to assess the development of the main clinical outcomes (postoperative delirium and delayed neurocognitive recovery ...
N. V. Ermokhina, A. N. Kuzovlev, D.  V. Davydov, A. V. Grechko, P. A. Polyakov, P. V. Ryzhkov, T.  S. Serkova, E. A. Lukyanova, D. V. Belokopytov, V. V. Moroz   +9 more
doaj   +1 more source

Evaluación de la influencia de la agitación para la producción de biomasa microalgal en un fotobiorreactor panel plano a escala laboratorio

Mutis, 2020
Se evaluó la influencia de la agitación sobre la producción de biomasa en un fotobiorreactor (FBR) panel plano mediante la modificación de los aspersores en el difusor.
Jennifer L. Doncel Núñez, Heidy L. Moreno Saboyá   +1 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Optimization of Pre-Inoculum, Fermentation Process Parameters and Precursor Supplementation Conditions to Enhance Apigenin Production by a Recombinant Streptomyces albus Strain

Fermentation, 2021
Streptomyces albus J1074-pAPI (Streptomyces albus-pAPI) is a recombinant strain constructed to biotechnologically produce apigenin, a flavonoid with interesting bioactive features that up to now has been manufactured by extraction from plants with long ...
Simona Barbuto Ferraiuolo, Odile Francesca Restaino, Ignacio Gutiérrez-del-Río, Riccardo Ventriglia, Marcella Cammarota, Claudio J. Villar, Felipe Lombó, Chiara Schiraldi   +7 more
doaj   +1 more source

Effect of Axial Agitator Configuration (Up-Pumping, Down-Pumping, Reverse Rotation) on Flow Patterns Generated in Stirred Vessels [PDF]

, 2001
Single phase turbulent flow in a tank stirred with two different axial impellers - a pitched blade turbine (PBT) and a Mixel TT (MTT)- has been studied using Laser Doppler Velocimetry. The effect of the agitator configuration, i.e.
Fletcher, David F., Mavros, Paul, Aubin, Joelle, Xuereb, Catherine, Bertrand, Joël   +4 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A new approach to the prevention and treatment of delirium in elderly patients in the intensive care unit [PDF]

Journal of Community Hospital Internal Medicine Perspectives, 2015
The pronounced prevalence of delirium in geriatric patients admitted to the intensive care unit (ICU) and its increased morbidity and mortality is a well-established phenomenon.
Andrew B. Rosenzweig, Charmian D. Sittambalam   +1 more
doaj   +1 more source