Results 61 to 70 of about 21,307 (186)

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

open access: yesBritish Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral   +3 more
wiley   +1 more source

Dynamic reprogramming of DNA methylation at an epigenetically sensitive allele in mice.

open access: yesPLoS Genetics, 2006
There is increasing evidence in both plants and animals that epigenetic marks are not always cleared between generations. Incomplete erasure at genes associated with a measurable phenotype results in unusual patterns of inheritance from one generation to
Marnie E Blewitt   +4 more
doaj   +2 more sources

Omnivorous Behaviour of the Agouti (Dasyprocta leporina): A Neotropical Rodent with the Potential for Domestication

open access: yesScientifica, 2019
The agouti is a Neotropical rodent which is mainly utilized for its meat in rural communities. Recently, captive rearing of these animals by wildlife farmers have increased in the Neotropics.
Kegan Romelle Jones   +2 more
doaj   +1 more source

Impact of bauxite mining on mosquito communities (Diptera: Culicidae) and pathogen transmission risks in the eastern Amazon

open access: yesMedical and Veterinary Entomology, EarlyView.
Bauxite mining in the Amazon alters mosquito communities, favouring anthropophilic and generalist vectors while reducing species diversity and the variety of blood meal sources. Molecular analyses identified humans, tapirs and deer as the primary blood meal sources.
Mayron Mielly Morais Pacheco   +8 more
wiley   +1 more source

Cariotipo Citogenético de la Guagua (agouti paca) [PDF]

open access: yes, 1997
El presente trabajo reporta la dotación cromosómica de Agouti paca, una especie considerada en vía de extinción. Además, se muestra la estandarización de la técnica para la obtención de cromosomas en sangre periférica y el tiempo óptimo del pulso ...
López Ortiz, Juan Bautista   +5 more
core  

Abdominal B-mode and Doppler ultrasonography of chemically restrained agouti (Dasyprocta prymnolopha Wagler, 1831)

open access: yesPesquisa Veterinária Brasileira
: Agoutis are small-sized wild animals whose body weight can reach up to 4kg, and are found throughout Brazil. They are considered important seed dispersers, especially for big trees and there are species that rely almost exclusively on these animals for
Gerson T. Pessoa   +7 more
doaj   +1 more source

DM-MCDA: A web-based platform for data mining and multiple criteria decision analysis: A case study on road accident

open access: yesSoftwareX, 2019
Today’s ultra-connected world is generating a huge amount of data stored in databases and cloud environment especially in the era of transportation. These databases need to be processed and analyzed to extract useful information and present it as a valid
Addi Ait-Mlouk, Tarik Agouti
doaj   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

open access: yesObesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey   +7 more
wiley   +1 more source

Agouti Expression in Human Adipose Tissue: Functional Consequences and Increased Expression in Type 2 Diabetes [PDF]

open access: yes, 2003
It is well recognized that the agouti/melanocortin system is an important regulator of body weight homeostasis. Given that agouti is expressed in human adipose tissue and that the ectopic expression of agouti in adipose tissue results in moderately obese
Murrel, Angela   +6 more
core   +1 more source

Microbiome and Metabolomics in Obesity: Advances in Understanding and Interventions Across the Lifespan

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecourse dynamics from birth to older age, examines how GLP‐1‐based therapies ...
Ioanna Panagiota Kalafati   +12 more
wiley   +1 more source

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