Results 71 to 80 of about 21,307 (186)
Journal of Big Data, 2017 Data mining techniques and extracting patterns from large datasets play a vital role in knowledge discovery. Most of the decision makers encounter a large number of decision rules resulted from association rules mining.
Addi Ait-Mlouk +2 more
doaj +1 more source
Maternal obesity during lactation as a hypertensive cardiovascular risk factor in the offspring
Experimental Physiology, EarlyView.Abstract Maternal obesity is a major public health concern, with growing evidence supporting its role in the developmental programming of cardiometabolic disease. Although prenatal mechanisms have been investigated extensively, the contribution of lactation as a postnatal window of cardiovascular (CV) programming remains insufficiently understood ...
Gabriela Arenas +2 more
wiley +1 more source
Molecular characterization of the mouse agouti locus [PDF]
, 1994 The agouti locus in mouse chromosome 2 regulates the differential production of eumelanin (black or brown) and phaeomelanin (yellow) pigment granules. Agouti coloration, which is the true wild-type coat color of mice, arises because the individual hair ...
Bultman, Scott Justin
core
The Journal of Physiology, EarlyView.Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
Molecular Analysis of the Agouti Gene in Livestock
, 1998 Agouti alleles regulate pigmentation in mouse melanocytes causing the production of black and/or yellow coat color. Yellow allelic mutations result in the dysregulated overexpression of the agouti gene and promote a number of systemic disorders (lethal ...
Johansen, Marcus Dale
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Memorias do Instituto Oswaldo Cruz, 2007 Redescriptions are given of the mature oocysts of Eimeria aguti Carini 1935, E. cotiae Carini, 1935 and E. paraensis Carini, 1935, in the faeces of five specimens of the rodent Dasyprocta leporina (Rodentia: Dasyproctidae) from the state of Pará, North ...
Ralph Lainson +2 more
doaj
Mammary Diseases in a Captive Reared Agouti (Dasyprocta leporina) in Trinidad
Veterinary Sciences, 2020 The agouti (Dasyprocta leporina) is a neotropical rodent that is utilized for its meat by hunters as well as wildlife farmers. There is a dearth of information on infectious diseases that affect these animals.
Kegan Romelle Jones +3 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
Agouti and Agouti-related Proteins
, 2008 Agouti有多方面的意义。首先,它是分属几种不同物种的哺乳动物的俗称。其次,它是一些啮齿类动物的属名。第三,它代表了一种啮齿类动物特有的毛色。第四,它是一个与黑素皮质素受体信号转导途径的调控有关,存在于从人(Homo sapiens)到啮齿类动物,乃至斑马鱼(Danio rerio)的一个特定基因的名称,又是该基因产生的一种特定信号蛋白的名称。Agouti和Agouti相关蛋白是肿瘤、肥胖与糖尿病等人类疾病的研究热点之一。Agouti黄色肥胖小鼠最近成了表观遗传学研究的一个重要模型动物 ...
郭宗圣, 高丹玫, 杨云青
core
Agouti regulation of intracellular calcium: role of melanocortin receptors
, 1997 Several dominant mutations at the murine agouti locus cause a syndrome of marked obesity and insulin resistance. We have recently reported that intracellular free Ca2+ concentration ([Ca2+]i) is elevated in viable yellow mice.
M. B. Zemel +8 more
core +1 more source