Results 41 to 50 of about 35,097 (228)

Hypothalamic gene expression during voluntary hypophagia in the Sprague-Dawley rat on withdrawal of the palatable liquid diet, Ensure [PDF]

open access: yes, 2014
Copyright © 2014 Elsevier Inc.
Archer, Zoe A   +2 more
core   +1 more source

Pleiotropic effects of a methyl donor diet in a novel animal model. [PDF]

open access: yesPLoS ONE, 2014
Folate and other methyl-donor pathway components are widely supplemented due to their ability to prevent prenatal neural tube defects. Several lines of evidence suggest that these supplements act through epigenetic mechanisms (e.g.
Kimberly R Shorter   +8 more
doaj   +1 more source

Understanding pseudo-albinism in sole (Solea senegalensis): a transcriptomics and metagenomics approach [PDF]

open access: yes, 2019
Pseudo-albinism is a pigmentation disorder observed in flatfish aquaculture with a complex, multi-factor aetiology. We tested the hypothesis that pigmentation abnormalities are an overt signal of more generalised modifications in tissue structure and ...
Carballo, Carlos   +7 more
core   +1 more source

Estimation, morphometry and ultrastructure of ovarian preantral follicle population in agouti (Dasyprocta leporina)

open access: yesPesquisa Veterinária Brasileira
: The aim of this study was to characterize the preantral ovarian follicular population in agoutis (D. leporina) by estimating the number of follicles at each developmental category, and also describe the morphometry and the specific features of the ...
Erica A.A. Santos   +7 more
doaj   +1 more source

Humans are not unique: difficult birth is common in placental mammals

open access: yesBiological Reviews, EarlyView.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Structural and Molecular Evolutionary Analysis of Agouti and Agouti-Related Proteins

open access: yesChemistry & Biology, 2006
Agouti (ASIP) and Agouti-related protein (AgRP) are endogenous antagonists of melanocortin receptors that play critical roles in the regulation of pigmentation and energy balance, respectively, and which arose from a common ancestral gene early in vertebrate evolution.
Jackson, Pilgrim J.   +6 more
openaire   +2 more sources

Regulation of leptin by agouti [PDF]

open access: yesPhysiological Genomics, 2000
Claycombe, Kate J., Bing Zhong Xue, Randall L. Mynatt, Michael B. Zemel, and Naïma Moustaïd-Moussa. Regulation of leptin by agouti. Physiol Genomics 2: 101–105, 2000.—Dominant mutations at the mouse Agouti locus lead to ectopic expression of the Agouti gene and exhibit diabetes, obesity, and yellow coat color. Obese yellow mice are hyperinsulinemic and
K J, Claycombe   +4 more
openaire   +2 more sources

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

open access: yesPediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil   +2 more
wiley   +1 more source

Wildlife temporal behaviors in response to human activity changes during and following COVID‐19 park closures

open access: yesWildlife Biology, EarlyView.
With urbanization reducing the amount of available wildlife habitat, and outdoor recreation increasing the human activity within wildlife habitats, it is important to understand the effects of human activity on animal behavior. This study examined how the reduction in human presence in urban parks in Gainesville, Florida, affected the temporal ...
Maya Fives, Matthew Hallett
wiley   +1 more source

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