Agouti Signaling Protein and Its Receptors as Potential Molecular Markers for Intramuscular and Body Fat Deposition in Cattle [PDF]
Frontiers in Physiology, 2018 Transcriptome analyses of bovine muscle tissue differing in intramuscular fat (IMF) content identified agouti signaling protein (ASIP) as a promising candidate gene for fat deposition.
Yinuo Liu +7 more
doaj +4 more sources
Frontiers in Endocrinology, 2022 Agouti-related protein (AgRP) is a neuropeptide synthesized by AgRP/NPY neurons and transcribed as 132 amino acids in humans and 142 amino acids (AgRP1) in Japanese seabass (Lateolabrax maculatus) fish.
Juan Han +5 more
doaj +3 more sources
Blocking ASIP to Protect MC1R Signaling and Mitigate Melanoma Risk: An In Silico Study [PDF]
PharmaceuticalsBackground: Melanin protects skin and hair from the effects of ultraviolet (UV) radiation damage, which contributes to all forms of skin cancer, including melanoma.
Farah Maarfi +3 more
doaj +2 more sources
Glucose Intake during the Neonatal Period Modulates the Central Melanocortin System with Breed-Specific Differences [PDF]
The Journal of Poultry ScienceGlucose is the primary substrate for cellular energy production, and its blood concentration is tightly regulated. This study investigated the effect of glucose supplementation during the first three days post-hatching on growth performance and ...
Kazuki Kimura +6 more
doaj +2 more sources
Agouti-signaling protein (ASIP) improves bovine in vitro matured oocyte developmental competence and modulates lipid content [PDF]
Journal of Assisted Reproduction and GeneticsJianbo Yao, Yao Jianbo
exaly +2 more sources
Integration of Nutrient Sensing in Fish Hypothalamus
Frontiers in Neuroscience, 2021 The knowledge regarding hypothalamic integration of metabolic and endocrine signaling resulting in regulation of food intake is scarce in fish. Available studies pointed to a network in which the activation of the nutrient-sensing (glucose, fatty acid ...
José L. Soengas
doaj +1 more source
Role of the Melanocortin System in Gonadal Steroidogenesis of Zebrafish
Animals, 2022 In teleost, as in other vertebrates, stress affects reproduction. A key component of the stress response is the pituitary secretion of the adrenocorticotropic hormone (ACTH), which binds to the melanocortin 2 receptor (MC2R) in the adrenal glands and ...
Sandra Navarro +6 more
doaj +1 more source
The Journal of Poultry Science, 2022 Previous studies in mammalian obesity models have suggested that central transforming growth factor-β (TGF-β) controls the gene expression of appetite-regulating neuropeptides and peripheral energy metabolism.
Takaoki Saneyasu +5 more
doaj +1 more source
Melanism in peromyscus is caused by independent mutations in agouti. [PDF]
PLoS ONE, 2009 Identifying the molecular basis of phenotypes that have evolved independently can provide insight into the ways genetic and developmental constraints influence the maintenance of phenotypic diversity.
Evan P Kingsley +3 more
doaj +1 more source
Coat colour phenotype of Qingyu pig is associated with polymorphisms of melanocortin receptor 1 gene [PDF]
Asian-Australasian Journal of Animal Sciences, 2017 Objective Qingyu pig, a Chinese indigenous pig breed, exhibits two types of coat colour phenotypes, including pure black and white with black spotting respectively.
Xiaoqian Wu +11 more
doaj +1 more source