Results 21 to 30 of about 9,208 (167)

Genetic characterization of coat color genes in Brazilian Crioula sheep from a conservation nucleus [PDF]

open access: yesPesquisa Agropecuária Brasileira, 2017
: The objective of this work was to identify single nucleotide polymorphisms (SNPs) in resequencing data from MC1R, ASIP, and TYRP1 genes derived from Crioula sheep (Ovis aris) with different coat colors.
Lilian Cristina Gomes Cavalcanti   +7 more
doaj   +1 more source

PDK1-Foxo1 in agouti-related peptide neurons regulates energy homeostasis by modulating food intake and energy expenditure. [PDF]

open access: yesPLoS ONE, 2011
Insulin and leptin intracellular signaling pathways converge and act synergistically on the hypothalamic phosphatidylinositol-3-OH kinase/3-phosphoinositide-dependent protein kinase 1 (PDK1).
Yongheng Cao   +17 more
doaj   +1 more source

Adaptive variation in beach mice produced by two interacting pigmentation genes.

open access: yesPLoS Biology, 2007
Little is known about the genetic basis of ecologically important morphological variation such as the diverse color patterns of mammals. Here we identify genetic changes contributing to an adaptive difference in color pattern between two subspecies of ...
Cynthia C Steiner   +2 more
doaj   +1 more source

Hypothalamic mTOR signaling mediates the orexigenic action of ghrelin.

open access: yesPLoS ONE, 2012
Current evidence suggests that ghrelin, a stomach derived peptide, exerts its orexigenic action through specific modulation of Sirtuin1 (SIRT1)/p53 and AMP-activated protein kinase (AMPK) pathways, which ultimately increase the expression of agouti ...
Luís Martins   +7 more
doaj   +1 more source

Local Agouti Signaling Protein/Melanocortin Signaling System that Possibly Regulates Lipid Metabolism in Adipose Tissues of Chickens

open access: yesThe Journal of Poultry Science, 2010
The agouti signaling protein (ASIP)/melanocortin signaling system regulates lipid metabolism in humans but not in mice. To examine whether the system is present in adipose tissues in chickens, we performed reverse transcription-polymerase chain reaction
Masafumi Yabuuchi   +4 more
doaj   +1 more source

The differential expression of MC1R regulators in dorsal and ventral quail plumages during embryogenesis: Implications for plumage pattern formation. [PDF]

open access: yesPLoS ONE, 2017
Melanin pigmentation patterns are ubiquitous in animals and function in crypsis, physical protection, thermoregulation and signalling. In vertebrates, pigmentation patterns formed over large body regions as well as within appendages (hair/feathers) may ...
Thanh-Lan Gluckman, Nicholas I Mundy
doaj   +1 more source

Anti-inflammatory effects of hunger are transmitted to the periphery via projection-specific AgRP circuits

open access: yesCell Reports, 2023
Summary: Caloric restriction has anti-inflammatory effects. However, the coordinated physiological actions that lead to reduced inflammation in a state of caloric deficit (hunger) are largely unknown.
Michelle L. Klima   +7 more
doaj   +1 more source

Ribosomal S6K1 in POMC and AgRP Neurons Regulates Glucose Homeostasis but Not Feeding Behavior in Mice

open access: yesCell Reports, 2015
Hypothalamic ribosomal S6K1 has been suggested as a point of convergence for hormonal and nutrient signals in the regulation of feeding behavior, bodyweight, and glucose metabolism.
Mark A. Smith   +11 more
doaj   +1 more source

Standardization of Methodology for Polymorphism Detection in ASIP, MC1R and MATP Genes in Relation to Colour in Horses

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2017
The basic colour in horses, such as black, brown and chestnut is affected by only two genes MC1R and ASIP. Other colours in horses are affected by modifying genes, such as dilution gene MATP.
Eliška Horecká   +2 more
doaj   +1 more source

Hypothalamic GHR—SIRT1 Axis in Fasting

open access: yesCells, 2021
Many aspects of physiological functions are controlled by the hypothalamus, a brain region that connects the neuroendocrine system to whole-body metabolism.
Juliana Bezerra Medeiros de Lima   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy