Results 1 to 10 of about 599,754 (328)

Variability of the medullary arcuate nucleus in humans [PDF]

Brain and Behavior, 2018
AbstractIntroductionThe arcuate nucleus is a component of the ventral medullary surface involved in chemoreception and breathing control. The hypoplasia of this nucleus is a very frequent finding in victims of sudden unexplained fetal and infant death (from the last weeks of pregnancy to the first year of life).
Ferrero, S, Lavezzi, Am, Paradiso, B, Thiene, G   +3 more
core   +5 more sources

Arcuate Nucleus-Dependent Regulation of Metabolism-Pathways to Obesity and Diabetes Mellitus.

Endocr Rev, 2022
The central nervous system (CNS) receives information from afferent neurons, circulating hormones, and absorbed nutrients and integrates this information to orchestrate the actions of the neuroendocrine and autonomic nervous systems in maintaining ...
Jais A, Brüning JC.
europepmc   +4 more sources

Suprachiasmatic Nucleus Interaction with the Arcuate Nucleus; Essential for Organizing Physiological Rhythms [PDF]

eneuro, 2017
AbstractThe suprachiasmatic nucleus (SCN) is generally considered the master clock, independently driving all circadian rhythms. We recently demonstrated the SCN receives metabolic and cardiovascular feedback adeptly altering its neuronal activity.
Frederik N. Buijs, Mara Guzmán-Ruiz, Luis León-Mercado, Mari Carmen Basualdo, Carolina Escobar, Andries Kalsbeek, Ruud M. Buijs   +6 more
openaire   +4 more sources

Suprachiasmatic Nucleus–Arcuate Nucleus Axis: Interaction Between Time and Metabolism Essential for Health [PDF]

Obesity, 2020
In mammals, time and metabolism are tightly coupled variables; this relationship can be illustrated by numerous examples, such as the circadian variation in food intake or the circadian response to a glucose bolus. We review evidence that the interaction between the suprachiasmatic nucleus and the arcuate nucleus plays a key role in the execution of ...
Rebeca Méndez‐Hernández, Carolina Escobar, Ruud M. Buijs   +2 more
openaire   +3 more sources

Regulation of Feeding Behavior and Body Weight by Orexigenic Neurons in the Arcuate Nucleus [PDF]

Journal of Obesity & Metabolic Syndrome
The arcuate nucleus of the hypothalamus is arguably the most important nucleus for regulating energy homeostasis and metabolism. Since its initial description in the human brain, its function in metabolic regulation has been studied extensively.
Yu Fu
doaj   +2 more sources

Mapping neuronal inputs to Kiss1 neurons in the arcuate nucleus of the mouse.

PLoS ONE, 2019
The normal function of the mammalian reproductive axis is strongly influenced by physiological, metabolic and environmental factors. Kisspeptin neuropeptides, encoded by the Kiss1 gene, are potent regulators of the mammalian reproductive axis by ...
Shel-Hwa Yeo, Victoria Kyle, Clemence Blouet, Susan Jones, William Henry Colledge   +4 more
doaj   +2 more sources

Arcuate Nucleus of the Hypothalamus: Anatomy, Physiology, and Diseases. [PDF]

Exp Neurobiol, 2023
The hypothalamus is part of the diencephalon and has several nuclei, one of which is the arcuate nucleus. The arcuate nucleus of hypothalamus (ARH) consists of neuroendocrine neurons and centrally-projecting neurons. The ARH is the center where the homeostasis of nutrition/metabolism and reproduction are maintained.
Song J, Choi SY.
europepmc   +3 more sources

Knockdown of Mct1 in the arcuate nucleus increases food-anticipatory activity in mice [PDF]

Frontiers in Physiology
Animals rely on internal time-keeping mechanisms to anticipate regular events such as feeding, allowing preemptive gene expression which enables timely physiological responses. A manifestation of anticipatory mechanisms is also a rise in body temperature
Tomaz Martini, Tomaz Martini, Urs Albrecht   +2 more
doaj   +2 more sources

Developmental Switch of Leptin Signaling in Arcuate Nucleus Neurons [PDF]

Journal of Neuroscience, 2014
Leptin is well known for its role in the regulation of energy homeostasis in adults, a mechanism that at least partially results from the inhibition of the activity of NPY/AgRP/GABA neurons (NAG) in the arcuate nucleus of the hypothalamus (ARH). During early postnatal development in the rodent, leptin promotes axonal outgrowth from ARH neurons, and ...
Arian F, Baquero, Alain J, de Solis, Sarah R, Lindsley, Melissa A, Kirigiti, M Susan, Smith, Michael A, Cowley, Lori M, Zeltser, Kevin L, Grove   +7 more
openaire   +3 more sources

Glucokinase activity in the arcuate nucleus regulates glucose intake [PDF]

Journal of Clinical Investigation, 2014
The brain relies on a constant supply of glucose, its primary fuel, for optimal function. A taste-independent mechanism within the CNS that promotes glucose delivery to the brain has been postulated to maintain glucose homeostasis; however, evidence for such a mechanism is lacking.
Hussain, Syed, Richardson, Errol, Ma, Yue, Holton, Christopher, De Backer, Ivan, Buckley, Niki, Dhillo, Waljit, Bewick, Gavin, Zhang, Shuai, Carling, David, Bloom, Steve, Gardiner, James   +11 more
openaire   +5 more sources