Results 31 to 40 of about 599,754 (328)

Morphological evidence for enhanced kisspeptin and neurokinin B signaling in the infundibular nucleus of the aging man. [PDF]

, 2012
Peptidergic neurons synthesizing kisspeptin (KP) and neurokinin B (NKB) in the hypothalamic infundibular nucleus have been implicated in negative sex steroid feedback to GnRH neurons. In laboratory rodents, testosterone decreases KP and NKB expression in
Bloom, Stephen R., Borsay, Beáta Á., Ciofi, Philippe, Dhillo, Waljit S., Ghatei, Mohammad A., Herczeg, László, Hrabovszky, Erik, Liposits, Zsolt, Molnár, Csilla S., Rácz, Kálmán, Sipos, Máté T., Vida, Barbara   +11 more
core   +1 more source

Investigating the KNDy hypothesis in humans by co-administration of kisspeptin, neurokinin B and naltrexone in men [PDF]

, 2016
Context: A subpopulation of hypothalamic neurons co-localise three neuropeptides namely kisspeptin, neurokinin B (NKB) and dynorphin collectively termed KNDy neurons. Animal studies suggest they interact to affect pulsatile GnRH release (KNDy hypothesis);
Abbara, A, Bassett, P, Bloom, S, COMNINOS, A, Dhillo, WS, Jayasena, C, Mizamtsidi, M, Narayanaswamy, S, Papadopoulou, D, Prague, J, Shah, A, Veldhuis, J   +11 more
core   +1 more source

Ablation of the Leptin Receptor in the Hypothalamic Arcuate Nucleus Abrogates Leptin-Induced Sympathetic Activation

Circulation Research, 2011
S. Harlan, D. Morgan, K. Agassandian, D. Guo, M. Cassell, C. Sigmund, A. Mark, K. Rahmouni   +7 more
semanticscholar   +3 more sources

Kisspeptin Neurons in the Arcuate Nucleus of the Hypothalamus Orchestrate Circadian Rhythms and Metabolism.

Current Biology, 2019
Successful reproduction in female mammals is precisely timed and must be able to withstand the metabolic demand of pregnancy and lactation. We show that kisspeptin-expressing neurons in the arcuate hypothalamus (Kiss1ARH) of female mice control the daily
Stephanie L. Padilla, Jazmine G. Perez, Miriam Ben-Hamo, C. W. Johnson, R. E. Sanchez, Ivana L. Bussi, R. Palmiter, H. O. de la Iglesia   +7 more
semanticscholar   +1 more source

QRFP-Deficient Mice Are Hypophagic, Lean, Hypoactive and Exhibit Increased Anxiety-Like Behavior. [PDF]

PLoS ONE, 2016
How the hypothalamus transmits hunger information to other brain regions to govern whole brain function to orchestrate feeding behavior has remained largely unknown.
Kitaro Okamoto, Miwako Yamasaki, Keizo Takao, Shingo Soya, Monica Iwasaki, Koh Sasaki, Kenta Magoori, Iori Sakakibara, Tsuyoshi Miyakawa, Michihiro Mieda, Masahiko Watanabe, Juro Sakai, Masashi Yanagisawa, Takeshi Sakurai   +13 more
doaj   +1 more source

Tyrosine Hydroxylase Expression in Differentiating Neurons of the Rat Arcuate Nucleus: Stimulatory Influence of Serotonin Afferents

Neural Plasticity, 2001
The influence of serotonin afferents on tyrosine hydroxylase expression in differentiating neurons of the rat arcuate nucleus was studied in vivo and in vitro.
Viktoria I. Melnikova, Michael V. Ugrumov, Evgenia V. Proshlyakova, André Calas, Jean Thibault   +4 more
doaj   +1 more source

Hunger and Satiety Gauge Reward Sensitivity

Frontiers in Endocrinology, 2017
Many of the neurocircuits and hormones known to underlie the sensations of hunger and satiety also substantially alter the activity of the dopaminergic reward system.
Ryan Michael Cassidy, Qingchun Tong
doaj   +1 more source

Effect of hyperthyroidism on circulating prolactin and hypothalamic expression of tyrosine hydroxylase, prolactin signaling cascade members and estrogen and progesterone receptors during late pregnancy and lactation in the rat [PDF]

, 2017
Hyperthyroidism (HyperT) compromises pregnancy and lactation, hindering suckling-induced PRL release. We studied the effect of HyperT on hypothalamic mRNA (RT-qPCR) and protein (Western blot) expression of tyrosine hydroxylase (TH), PRL receptor (PRLR ...
Jahn, Graciela Alma, Neira, Flavia Judith, Pennacchio, Gisela Erika, Soaje, Marta, Valdez, Susana Ruth   +4 more
core   +1 more source

Acute Suppression of LH Secretion by Prolactin in Female Mice Is Mediated by Kisspeptin Neurons in the Arcuate Nucleus.

Endocrinology, 2019
Hyperprolactinemia causes infertility, but the specific mechanism is unknown. It is clear that elevated prolactin levels suppress pulsatile release of GnRH from the hypothalamus, with a consequent reduction in pulsatile LH secretion from the pituitary ...
R. Brown, Zin Khant Aung, Hollian R Phillipps, Z. Barad, Hsin-Jui Lein, U. Boehm, R. Szawka, D. Grattan   +7 more
semanticscholar   +1 more source

Arcuate nucleus glucokinase and dietary glucose intake

Oncotarget, 2015
Glucose is the primary fuel for the brain. It has been proposed that the brain senses glucose, and promotes eating behaviours when levels are low. A system regulating glucose intake, driven by hedonic responses generated in the limbic system, has been identified.
Ma, Y, Bloom, SR, Gardiner, JV
openaire   +4 more sources