It has been proved that arterial hypertension is not associated exclusively with an increase in vascular tone but also with a complex of pathological processes that results in cardiovascular pathology and lesions of the target organs.
S. V. Tishchenko
doaj +3 more sources
Substance p immunoreactivity exhibits frequent colocalization with kisspeptin and neurokinin B in the human infundibular region. [PDF]
Neurons synthesizing neurokinin B (NKB) and kisspeptin (KP) in the hypothalamic arcuate nucleus represent important upstream regulators of pulsatile gonadotropin-releasing hormone (GnRH) neurosecretion.
Herczeg, László +35 more
core +1 more source
Short photoperiod-induced decrease of histamine H3 receptors facilitates activation of hypothalamic neurons in the Siberian Hamster [PDF]
Nonhibernating seasonal mammals have adapted to temporal changes in food availability through behavioral and physiological mechanisms to store food and energy during times of predictable plenty and conserve energy during predicted shortage.
Bartness, Timothy J. +7 more
core +1 more source
Investigating the role of arcuate nucleus and paraventricular nucleus glucokinase in glucose homeostasis [PDF]
The brain is as an important regulator of appetite and metabolism. Glucokinase (GK) is a key component of glucose sensing, and is expressed in many glucose sensitive neurones (Rosario et al., 2016, Pocai et al., 2005b).
Ratnasabapathy, Risheka
core +1 more source
Hypothalamic arcuate nucleus glucokinase regulates insulin secretion and glucose homeostasis [PDF]
Aims Glucokinase (GK) serves as a glucose sensor in several tissues including glucose‐sensitive neurons of the arcuate nucleus within the hypothalamus.
Ma, Yue +42 more
core +1 more source
QRFP-Deficient Mice Are Hypophagic, Lean, Hypoactive and Exhibit Increased Anxiety-Like Behavior. [PDF]
How the hypothalamus transmits hunger information to other brain regions to govern whole brain function to orchestrate feeding behavior has remained largely unknown.
Kitaro Okamoto +13 more
doaj +1 more source
Glucokinase activity in the arcuate nucleus regulates glucose intake [PDF]
The brain relies on a constant supply of glucose, its primary fuel, for optimal function. A taste-independent mechanism within the CNS that promotes glucose delivery to the brain has been postulated to maintain glucose homeostasis; however, evidence for ...
Niki Buckley +35 more
core +1 more source
Hunger and Satiety Gauge Reward Sensitivity
Many of the neurocircuits and hormones known to underlie the sensations of hunger and satiety also substantially alter the activity of the dopaminergic reward system.
Ryan Michael Cassidy, Qingchun Tong
doaj +1 more source
Context: That serotonin plays a role in the regulation of feeding behavior and energy metabolism has been known for a long time. Serotonin transporters (SERT) play a crucial role in serotonin signalling by regulating its availability in the synaptic ...
Anke eBorgers +7 more
doaj +1 more source
Prolyl carboxypeptidase in Agouti-related Peptide neurons modulates food intake and body weight
Objective: Prolyl carboxypeptidase (PRCP) plays a role in the regulation of energy metabolism by inactivating hypothalamic α-melanocyte stimulating hormone (α-MSH) levels.
Giuseppe Bruschetta +3 more
doaj +1 more source

