Relative number and distribution of murine hypothalamic proopiomelanocortin neurons innervating distinct target sites. [PDF]
PLoS ONE, 2011 Proopiomelanocortin (POMC) neurons send projections widely throughout the brain consistent with their role in regulating numerous homeostatic processes and mediating analgesia and reward.
Connie M King, Shane T Hentges
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Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice
Nature Communications, 2023 Coupling the release of pituitary hormones to the developmental stage of the oocyte is essential for female fertility. It requires estrogen to restrain kisspeptin (KISS1)-neuron pulsatility in the arcuate hypothalamic nucleus, while also exerting a surge-
Jose M. Ramos-Pittol +14 more
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NPY and VGF immunoreactivity increased in the arcuate nucleus, but decreased in the nucleus of the Tractus Solitarius, of type-II diabetic patients. [PDF]
PLoS ONE, 2012 Ample animal studies demonstrate that neuropeptides NPY and α-MSH expressed in Arcuate Nucleus and Nucleus of the Tractus Solitarius, modulate glucose homeostasis and food intake. In contrast is the absence of data validating these observations for human
Nadia Saderi +8 more
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GABAergic RIP-Cre neurons in the arcuate nucleus selectively regulate energy expenditure.
Cell, 2012 D. Kong +9 more
semanticscholar +3 more sources
Ventromedial Arcuate Nucleus Communicates Peripheral Metabolic Information to the Suprachiasmatic Nucleus [PDF]
Endocrinology, 2006 The arcuate nucleus (ARC) is crucial for the maintenance of energy homeostasis as an integrator of long- and short-term hunger and satiety signals. The expression of receptors for metabolic hormones, such as insulin, leptin, and ghrelin, allows ARC to sense information from the periphery and signal it to the central nervous system. The ventromedial ARC
Yi, Chun-Xia +5 more
openaire +4 more sources
Molecular Pain, 2020 Aims The arcuate nucleus is a vital brain region for coursing of pain command. G protein-coupled kinase 6 (GRK6) accommodates signaling through G protein-coupled receptors.
Xin Li +7 more
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Oxytocin signaling in the posterior hypothalamus prevents hyperphagic obesity in mice
eLife, 2022 Decades of studies have revealed molecular and neural circuit bases for body weight homeostasis. Neural hormone oxytocin (Oxt) has received attention in this context because it is produced by neurons in the paraventricular hypothalamic nucleus (PVH), a ...
Kengo Inada +4 more
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Journal of Education, Health and Sport, 2019 It has been proved that arterial hypertension is not associated exclusively with an increase in vascular tone but also with a complex of pathological processes that results in cardiovascular pathology and lesions of the target organs.
S. V. Tishchenko
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Short photoperiod-induced decrease of histamine H3 receptors facilitates activation of hypothalamic neurons in the Siberian Hamster [PDF]
, 2009 Nonhibernating seasonal mammals have adapted to temporal changes in food availability through behavioral and physiological mechanisms to store food and energy during times of predictable plenty and conserve energy during predicted shortage.
Bamshad +46 more
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Hypothalamic Vitamin D Improves Glucose Homeostasis and Reduces Weight [PDF]
, 2016 Despite clear associations between vitamin D deficiency and obesity and/or type 2 diabetes, a causal relationship is not established. Vitamin D receptors (VDRs) are found within multiple tissues, including the brain.
Arble, Deanna M. +9 more
core +4 more sources