Regulation of Feeding Behavior and Body Weight by Orexigenic Neurons in the Arcuate Nucleus [PDF]
Journal of Obesity & Metabolic SyndromeThe arcuate nucleus of the hypothalamus is arguably the most important nucleus for regulating energy homeostasis and metabolism. Since its initial description in the human brain, its function in metabolic regulation has been studied extensively.
Yu Fu
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Tyrosine Hydroxylase Expression in Differentiating Neurons of the Rat Arcuate Nucleus: Stimulatory Influence of Serotonin Afferents [PDF]
Neural Plasticity, 2001 The influence of serotonin afferents on tyrosine hydroxylase expression in differentiating neurons of the rat arcuate nucleus was studied in vivo and in vitro.
Viktoria I. Melnikova +4 more
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NPY and VGF immunoreactivity increased in the arcuate nucleus, but decreased in the nucleus of the Tractus Solitarius, of type-II diabetic patients. [PDF]
PLoS ONE, 2012 Ample animal studies demonstrate that neuropeptides NPY and α-MSH expressed in Arcuate Nucleus and Nucleus of the Tractus Solitarius, modulate glucose homeostasis and food intake. In contrast is the absence of data validating these observations for human
Nadia Saderi +8 more
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Basic and Clinical Neuroscience, 2020 Introduction: Broad neural circuits originate from the hypothalamic arcuate nucleus and project to many parts of the brain which are related to pain perception. Insulin receptors are found in the arcuate nucleus. Since nociception may be affected in type
Hossein Khaleghzadeh-Ahangar +4 more
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Knockdown of Mct1 in the arcuate nucleus increases food-anticipatory activity in mice [PDF]
Frontiers in PhysiologyAnimals rely on internal time-keeping mechanisms to anticipate regular events such as feeding, allowing preemptive gene expression which enables timely physiological responses. A manifestation of anticipatory mechanisms is also a rise in body temperature
Tomaz Martini +2 more
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Knocking down the neuronal lactate transporter MCT2 in the arcuate nucleus of female rats increases food intake and body weight [PDF]
Scientific ReportsIn the arcuate nucleus of the hypothalamus, tanycyte-neuron interactions regulate glucose homeostasis and feeding behavior. Previously, we reported that monocarboxylate transporters (MCT) 1 and 4 are localized in tanycytes, whereas MCT2 is present in ...
Alanis Coca +10 more
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Modulating effect of irisin on the functional state of inhibitory afferent inputs to the suprachiasmatic nucleus from the arcuate nucleus [PDF]
BIO Web of ConferencesIn vitro experiments on viable hypothalamic slices of male Wistar rats, the modulating effect of the myokine irisin on the parameters of inhibitory responses of neurons in the suprachiasmatic nucleus to stimulation of the arcuate nucleus was studied.
Inyushkin Alexey +4 more
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Cannabinoid type 1 receptor-containing axons innervate NPY/AgRP neurons in the mouse arcuate nucleus [PDF]
Molecular Metabolism, 2017 Objectives: Phytocannabinoids, such as THC and endocannabinoids, are well known to promote feeding behavior and to control energy metabolism through cannabinoid type 1 receptors (CB1R).
Yury M. Morozov +3 more
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The restorative effect of platelet-rich plasma on estrous cycle disruption induced by arcuate nucleus lesion in female Wistar rats: An experimental study [PDF]
International Journal of Reproductive BioMedicineBackground: Successful reproduction relies on a functioning hypothalamic-pituitary-gonad axis. Damage to this axis disrupts the estrus cycle and reproductive capability.
Elham Abbasi +3 more
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Arcuate Nucleus-Dependent Regulation of Metabolism-Pathways to Obesity and Diabetes Mellitus.
Endocrine Reviews, 2022 Jens Claus Brüning, Alexander Jais
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