Results 51 to 60 of about 599,754 (328)

Neuropeptide Y and Metabolism Syndrome: An Update on Perspectives of Clinical Therapeutic Intervention Strategies

open access: yesFrontiers in Cell and Developmental Biology, 2021
Through the past decade of research, the pathogenic mechanisms underlying metabolic syndrome have been suggested to involve not only the peripheral tissues, but also central metabolic regulation imbalances.
Yinqiong Huang   +3 more
doaj   +1 more source

The Role of the Brain in the Pathogenesis and Physiology of Polycystic Ovary Syndrome (PCOS). [PDF]

open access: yes, 2019
Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder, affecting at least 10% of women of reproductive age. PCOS is typically characterized by the presence of at least two of the three cardinal features of hyperandrogenemia (high ...
Coutinho, Eulalia A   +1 more
core   +1 more source

Insulin within the Arcuate Nucleus Has Paradoxical Effects on Nociception in Healthy and Diabetic Rats

open access: yesBasic and Clinical Neuroscience, 2020
Introduction: Broad neural circuits originate from the hypothalamic arcuate nucleus and project to many parts of the brain which are related to pain perception. Insulin receptors are found in the arcuate nucleus. Since nociception may be affected in type
Hossein Khaleghzadeh-Ahangar   +4 more
doaj  

Hypertrophy of the Anterior External Arcuate Fasciculus: A Rare Variant With Implications for the Development of the Arcuate Nucleus

open access: yesFrontiers in Neuroanatomy, 2020
A rare anatomic variant of a markedly enlarged anterior external arcuate fasciculus (AEAF) on the ventral medullary surface is reported and compared to two controls. The hypertrophic AEAF was nine times larger in diameter than normal, whereas the arcuate
Renee Stonebridge   +7 more
doaj   +1 more source

Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]

open access: yes, 2016
Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E.   +6 more
core   +1 more source

Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain. [PDF]

open access: yes, 2015
© 2015 The Authors.Objective: Although Glucagon-like peptide 1 is a key regulator of energy metabolism and food intake, the precise location of GLP-1 receptors and the physiological relevance of certain populations is debatable.
Cork, SC   +5 more
core   +2 more sources

Obesity: sex and sympathetics

open access: yesBiology of Sex Differences, 2020
Obesity increases sympathetic nerve activity (SNA) in men, but not women. Here, we review current evidence suggesting that sexually dimorphic sympathoexcitatory responses to leptin and insulin may contribute.
Zhigang Shi   +2 more
doaj   +1 more source

Developmental Changes in Synaptic Distribution in Arcuate Nucleus Neurons [PDF]

open access: yesThe Journal of Neuroscience, 2015
Neurons coexpressing neuropeptide Y, agouti-related peptide, and GABA (NAG) play an important role in ingestive behavior and are located in the arcuate nucleus of the hypothalamus. NAG neurons receive both GABAergic and glutamatergic synaptic inputs, however, the developmental time course of synaptic input organization of NAG neurons in mice is unknown.
Arian F. Baquero   +5 more
openaire   +2 more sources

Fetal alcohol exposure alters proopiomelanocortin gene expression and hypothalamic-pituitary-adrenal axis function via increasing MeCP2 expression in the hypothalamus. [PDF]

open access: yesPLoS ONE, 2014
Proopiomelanocortin (POMC) is a precursor gene of the neuropeptide β-endorphin in the hypothalamus and is known to regulate various physiological functions including stress response.
Omkaram Gangisetty   +3 more
doaj   +1 more source

Nesfatin-1 inhibits NPY neurons in the arcuate nucleus [PDF]

open access: yesBrain Research, 2008
Although the novel satiety factor nesfatin-1 has been shown to influence feeding behavior through effects on melanocortin signaling, the specific hypothalamic neuronal substrates through which such effects are mediated have yet to be elucidated. To identify neuronal cell types potentially important in mediating nesfatin-1's effects, whole cell current ...
Christopher J, Price   +2 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy