Results 71 to 80 of about 24,202 (294)

Angiotensin II AT1A receptor mRNA expression is induced by estrogen–progesterone in dopaminergic neurons of the female rat arcuate nucleus

open access: yes, 1997
Brain angiotensin II (Ang II) inhibits pituitary prolactin release by an indirect mechanism requiring stimulation of dopamine formation and release. We report that [125I]Sar1-Ang II binding to AT1 receptors and AT1A receptor mRNA expression increase ...
Egidy, Giorgia   +3 more
core   +2 more sources

A spontaneous leptin receptor point mutation causes obesity and differentially affects leptin signaling in hypothalamic nuclei resulting in metabolic dysfunctions distinct from db/db mice

open access: yesMolecular Metabolism, 2019
Objective: Leptin (Lep) plays a crucial role in controlling food intake and energy expenditure. Defective Lep/LepRb-signaling leads to fat accumulation, massive obesity, and the development of diabetes.
Federica Piattini   +7 more
doaj   +1 more source

Effects of liraglutide in hypothalamic arcuate nucleus of obese mice [PDF]

open access: yesObesity, 2016
ObjectiveThe neuroprotective effects of liraglutide (200 μg/kg, twice daily, subcutaneous administration) in the hypothalamic arcuate nucleus (ARC) of diet‐induced obese mice were investigated.MethodsC57BL/6 mice were separated into groups: standard chow treated with vehicle or liraglutide and the respective liraglutide pair‐fed group; high‐fat diet ...
Andre R C, Barreto-Vianna   +2 more
openaire   +2 more sources

Super‐Resolution Ultrasound Based Cell Tracking With Polymeric Nanobubbles

open access: yesAdvanced Materials, EarlyView.
This study presents a super‐resolution ultrasound platform for tracking cells in vivo. Biocompatible polymeric nanobubbles are used as highly echogenic intracellular labels. Following the injection of cells and microbubbles, ultrasound localization microscopy (ULM) can dynamically match the microvascular architecture and individual cell trajectories ...
Junlin Chen   +19 more
wiley   +1 more source

The arcuate nucleus of the C57BL/6J mouse hindbrain is a displaced part of the inferior olive

open access: yes, 2012
The arcuate nucleus is a prominent cell group in the human hindbrain, characterized by its position on the pial surface of the pyramid. It is considered to be a precerebellar nucleus and has been implicated in the pathology of several disorders of ...
Fu, Y.   +4 more
core   +1 more source

Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons

open access: yesNature Communications, 2018
In the hypothalamus, the arcuate nucleus (ARC) contains AgRP-neurons that regulate energy balance as well as GHRH-neurons that regulate linear growth. Here, the authors looked at how the transcription factors Dlx1/2 and Otp link development of AgRP- and ...
Bora Lee   +8 more
doaj   +1 more source

Cardiovascular Regulation by the Arcuate Nucleus of the Hypothalamus [PDF]

open access: yesHypertension, 2016
The importance of the central nervous system in cardiovascular regulation is well established.1,2 The brain is able to sense changes that occur in the peripheral circulation through several mechanisms, including afferent neural reflexes and humoral signals.
openaire   +2 more sources

Additive Manufacturing of Patient‐Specific Intracranial Aneurysm Cell Culture Models

open access: yesAdvanced Materials Technologies, EarlyView.
Patient‐specific intracranial aneurysm models were fabricated using chocolate moulding, 3D printed water‐soluble cores, and direct resin 3D printing. Moulding PDMS around sacrificial cores made of chocolate or 3D printed water‐soluble resin yielded accurate, expandable, and endothelializable models that outperformed resin‐based approaches.
Chloe M. de Nys   +6 more
wiley   +1 more source

Fasting induced cytoplasmic Fto expression in some neurons of rat hypothalamus. [PDF]

open access: yesPLoS ONE, 2013
Fat mass and obesity associated protein (Fto) is a nucleic acid demethylase, with a preference for thymine or uracil, according to the recent structural data. This fact suggests that methylated single-stranded RNA, rather than DNA, may be the primary Fto
Predrag Vujovic   +6 more
doaj   +1 more source

Molecular Properties of Kiss1 Neurons in the Arcuate Nucleus of the Mouse [PDF]

open access: yesEndocrinology, 2011
Neurons that produce kisspeptin play a critical role in reproduction. However, understanding the molecular physiology of kisspeptin neurons has been limited by the lack of an in vivo marker for those cells. Here, we report the development of a Kiss1-CreGFP knockin mouse, wherein the endogenous Kiss1 promoter directs the expression of a Cre recombinase ...
Michelle L, Gottsch   +12 more
openaire   +2 more sources

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