Results 1 to 10 of about 8,978 (173)
Molecular Metabolism, 2023 Objective: The sensory detection of food and food cues suppresses Agouti related peptide (AgRP) neuronal activity prior to consumption with greatest suppression occurring in response to highly caloric food or interoceptive energy need.
Wang Lok So +8 more
doaj +3 more sources
Drp1 is required for AgRP neuronal activity and feeding
eLife, 2021 The hypothalamic orexigenic Agouti-related peptide (AgRP)-expressing neurons are crucial for the regulation of whole-body energy homeostasis. Here, we show that fasting-induced AgRP neuronal activation is associated with dynamin-related peptide 1 (DRP1 ...
Sungho Jin +6 more
doaj +3 more sources
Changes in agouti-related protein and symptom improvement in drug-naïve Chinese female patients with anorexia nervosa: a 6-month real-world longitudinal study [PDF]
Journal of Eating DisordersBackground Agouti-related protein (AgRP) is an orexigenic neuropeptide that also plays a role in stereotypic behaviors and cognitive impairments. This study examined whether plasma AgRP levels are associated with eating disorder symptom severity and ...
Yanran Hu +8 more
doaj +2 more sources
Identification of AgRP cells in the murine hindbrain that drive feeding
Molecular MetabolismObjective: The central melanocortin system is essential for the regulation of food intake and body weight. Agouti-related protein (AgRP) is the sole orexigenic component of the central melanocortin system and is conserved across mammalian species.
Paul J Emmerson
exaly +3 more sources
A Small Potassium Current in AgRP/NPY Neurons Regulates Feeding Behavior and Energy Metabolism
Cell Reports, 2016 Neurons that co-express agouti-related peptide (AgRP) and neuropeptide Y (NPY) are indispensable for normal feeding behavior. Firing activities of AgRP/NPY neurons are dynamically regulated by energy status and coordinate appropriate feeding behavior to ...
Yanlin He, Gang Shu, Yongjie Yang
exaly +3 more sources
Dax1 in AgRP neurons regulates thermogenesis via GR-HDAC3-mediated CRFR1 suppression [PDF]
Molecular MetabolismObjectives: The arcuate nucleus of the hypothalamus plays a pivotal role in metabolic homeostasis by integrating the functions of AgRP and POMC neurons. Dax1, a nuclear receptor-like transcription factor, is highly enriched in AgRP neurons; however, its ...
Zhuodu Wei, Jooseon Cha, Seunghee Lee
doaj +2 more sources
Nutritive, Post-ingestive Signals Are the Primary Regulators of AgRP Neuron Activity
Cell Reports, 2017 Summary: The brain regulates food intake by processing sensory cues and peripheral physiological signals, but the neural basis of this integration remains unclear.
Zhenwei Su +2 more
exaly +3 more sources
Biomedicines, 2023 Neuronal circuits regulating appetite are dominated by arcuate nucleus neurons, which include appetite-promoting and -suppressing neurons that release the orexigenic neuropeptide agouti-related protein (AgRP) and anorexigenic neuropeptide pro ...
Chiu-Ya Lin +3 more
doaj +1 more source
Frontiers in Physiology, 2020 The orexigenic agouti-related protein (AgRP) and the anorexigenic pro-opiomelanocortin (POMC) are crucial players in the control of feed intake in vertebrates, yet their role in teleosts has not been fully established.
Tharmini Kalananthan +15 more
doaj +1 more source
Molecular Metabolism, 2023 Objective: The learned associations between sensory cues (e.g., taste, smell) and nutritive value (e.g., calories, post-ingestive signaling) of foods powerfully influences our eating behavior [1], but the neural circuits that mediate these associations ...
Nathaniel T. Nyema +6 more
doaj +1 more source