Results 1 to 10 of about 9,029 (175)

Ghrelin signalling in AgRP neurons links metabolic state to the sensory regulation of AgRP neural activity

open access: yesMolecular Metabolism, 2023
Objective: The sensory detection of food and food cues suppresses Agouti related peptide (AgRP) neuronal activity prior to consumption with greatest suppression occurring in response to highly caloric food or interoceptive energy need.
Wang Lok So   +8 more
doaj   +3 more sources

AgRP Neurons Regulate Bone Mass [PDF]

open access: yesCell Reports, 2015
The hypothalamus has been implicated in skeletal metabolism. Whether hunger-promoting neurons of the arcuate nucleus impact the bone is not known. We generated multiple lines of mice to affect AgRP neuronal circuit integrity. We found that mice with Ucp2
Jae Geun Kim   +7 more
doaj   +6 more sources

Drp1 is required for AgRP neuronal activity and feeding

open access: yeseLife, 2021
The hypothalamic orexigenic Agouti-related peptide (AgRP)-expressing neurons are crucial for the regulation of whole-body energy homeostasis. Here, we show that fasting-induced AgRP neuronal activation is associated with dynamin-related peptide 1 (DRP1 ...
Sungho Jin   +6 more
doaj   +3 more sources

Reanalysis of Evidence for/against AGRP in Korean [PDF]

open access: yesKansas Working Papers in Linguistics, 1998
This article deals with the controversial issue of AgrP in Korean within the Minimalist Program. Some linguists maintain that there is AgrP in Korean, while others not. In this article I review the evidence for and against the existence of AgrP in Korean,
Khym, Hangyoo
doaj   +2 more sources

AgRP neuronal activity across feeding‐related behaviours [PDF]

open access: yesEuropean Journal of Neuroscience, 2021
Abstract AgRP neurons trigger one of the most potent orexigenic responses and are both necessary and sufficient for feeding. Recent technical advances for monitoring in vivo neuronal activity have revisited a previously well‐established model of AgRP neurons' feeding regulatory effects.
Sophie Steculorum
exaly   +4 more sources

Identification of AgRP cells in the murine hindbrain that drive feeding

open access: yesMolecular Metabolism
Objective: The central melanocortin system is essential for the regulation of food intake and body weight. Agouti-related protein (AgRP) is the sole orexigenic component of the central melanocortin system and is conserved across mammalian species.
, Valdearcos M, Paul J Emmerson
exaly   +3 more sources

Changes in agouti-related protein and symptom improvement in drug-naïve Chinese female patients with anorexia nervosa: a 6-month real-world longitudinal study [PDF]

open access: yesJournal of Eating Disorders
Background Agouti-related protein (AgRP) is an orexigenic neuropeptide that also plays a role in stereotypic behaviors and cognitive impairments. This study examined whether plasma AgRP levels are associated with eating disorder symptom severity and ...
Yanran Hu   +8 more
doaj   +2 more sources

Mammalian comparative sequence analysis of the Agrp locus. [PDF]

open access: yesPLoS ONE, 2007
Agouti-related protein encodes a neuropeptide that stimulates food intake. Agrp expression in the brain is restricted to neurons in the arcuate nucleus of the hypothalamus and is elevated by states of negative energy balance.
Christopher B Kaelin   +3 more
doaj   +4 more sources

UCP2 mediates mitochondrial dynamics to induce AgRP neuronal activity

open access: yesMolecular Metabolism
Objectives: The hypothalamic agouti-related protein (AgRP)- expressing neurons regulate feeding and whole-body energy homeostasis. A growing body of evidence indicates that changes in mitochondrial dynamics, such as fission and fusion, play a crucial ...
Ciro Menale   +2 more
exaly   +3 more sources

Dax1 in AgRP neurons regulates thermogenesis via GR-HDAC3-mediated CRFR1 suppression [PDF]

open access: yesMolecular Metabolism
Objectives: The arcuate nucleus of the hypothalamus plays a pivotal role in metabolic homeostasis by integrating the functions of AgRP and POMC neurons. Dax1, a nuclear receptor-like transcription factor, is highly enriched in AgRP neurons; however, its ...
Zhuodu Wei, Jooseon Cha, Seunghee Lee
doaj   +2 more sources

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