Life-Threatening Agranulocytosis Induced by Sinomenine Hydrochloride in Chronic Kidney Disease: A Case Report and Literature Review. [PDF]
ABSTRACT Sinomenine, derived from Sinomenium acutum, is widely used in inflammatory diseases. However, its risk of inducing agranulocytosis is not widely appreciated. We report a life‐threatening case in a 40‐year‐old woman with chronic kidney disease (CKD; baseline estimated glomerular filtration rate [eGFR] as low as 36 mL/min/1.73 m2) who developed ...
Xin P, Liu R, Zhang Y, Fu B.
europepmc +2 more sources
Can propylthiouracil induce autoimmune-related immunotoxicity? [PDF]
Introduction. The use of propylthiouracil can be associated with mild adverse reactions, but severe complications such as agranulocytosis and vasculitis can also be seen.
Bajkin Ivana +4 more
doaj +1 more source
BACKGROUND: Carriers of germline pathogenic variants of the BRCA1 gene (gBRCA1) tend to have a higher incidence of haematological toxicity upon exposure to chemotherapy.
Noémie Lang +10 more
doaj +1 more source
Agranulocytosis in systemic lupus erythematosus: A case report
Agranulocytosis is a rare acute condition characterized by severe a
Olfa Frikha +6 more
doaj +1 more source
Successful Treatment of Neutropenia Associated With T-Cell Large Granular Lymphocytic Leukemia Using Fludarabine. [PDF]
T‐cell large granular lymphocytic leukemia (T‐LGLL) is an uncommon lymphoproliferative disorder that typically follows a slow clinical course. Symptoms often remain subtle until cytopenia or infection develops. Severe infection secondary to neutropenia represents the major cause of mortality.
Uemura Y, Togitani K, Kumon Y.
europepmc +2 more sources
Late onset clozapine induced agranulocytosis
Agranulocytosis is defined as an absolute neutrophil count less than 100/mm 3 in association with infectious disease. The risk of agranulocytosis is 0.38% of all clozapine treated cases and there is a relatively lesser incidence in Indian population. The
Rajmohan Velayudhan, Sushil Kakkan
doaj +1 more source
Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases. [PDF]
Exposure to levamisole-adulterated cocaine can induce a distinct clinical syndrome characterized by retiform purpura and/or agranulocytosis accompanied by an unusual constellation of serologic abnormalities including antiphospholipid antibodies, lupus ...
Butcher, Brad +6 more
core +2 more sources
Drug-Induced Neutropenia and Agranulocytosis
Drug-induced neutropenia and agranulocytosis are serious and potentially life-threatening complications of pharmacotherapy. The aim of the review was to systematise and analyse scientific literature on the prevalence, risk factors, pathogenesis, clinical
O. D. Ostroumova +3 more
doaj +1 more source
The measurement of health-related quality of life (QOL) in paediatric clinical trials: a systematic review [PDF]
Background The goal of much care in chronic childhood illness is to improve quality of life (QOL). However, surveys suggest QOL measures are not routinely included.
Clarke, S., Eiser, C.
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Pancreatitis following Olanzapine Therapy: A Report of Three Cases [PDF]
CONTEXT: Atypical antipsychotic agents (clozapine, olanzapine) have been linked to metabolic effects and acute pancreatitis. CASE REPORT: We reviewed the inpatient and outpatient records of three patients who developed acute pancreatitis while being ...
Azar, Riad +3 more
core +4 more sources

