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Antithyroid Drug-induced Agranulocytosis [PDF]
Antithyroid drugs are widely used to treat hyperthyroidism, especially Graves' disease, but they tend to cause agranulocytosis, which increases the mortality rate.
Sun, Ming-Tsung +2 more
core +1 more source
Antithyroid drugs can be a rare cause of agranulocytosis (0.5% of treated patients). Suspension of these drugs is mandatory in these patients and may result in worsening hyperthyroidism.
Anna Candoni
doaj +1 more source
Background/Purpose: Physicians' and dentists' knowledge of levamisole-induced agranulocytosis or pancytopenia remains incomplete. This study aimed to evaluate the treatment effectiveness of levamisole plus prednisolone on oral lichen planus (OLP ...
Shin-Yu Lu, Tzu-Fan Chang, Chih-Jen Lin
doaj +1 more source
Association of HLA-B∗38:02 with Antithyroid Drug-Induced Agranulocytosis in Kinh Vietnamese Patients
Background. HLA-B∗38:02 has been shown to be associated with antithyroid drug-induced agranulocytosis in Asian patients. Methods. HLA-B∗38:02 was analyzed by sequence-based typing in 21 patients who developed antithyroid drug-induced agranulocytosis and ...
Mai Phuong Thao +7 more
doaj +1 more source
Clozapine-induced agranulocytosis
Wider use of clozapine, one of the most effective antipshychotic drugs, is precluded by its propensity to cause agranulocytosis. Currently, clozapine is used for treatment-resistant schizophrenia, with mandatory blood count monitoring for the duration of
Mijovic, Aleksandar +1 more
core +1 more source
A population-based case-cohort study of drug-associated agranulocytosis
Background: Agranulocytosis is a life-threatening disorder, often caused by drugs. Incidences or risks of drug-induced agranulocytosis are not well known, since it is rare. Methods: To determine the risk of drug-associated agranulocytosis as a reason for
Van't Veer, Mars B. +6 more
core +3 more sources
Valproic Acid-induced Agranulocytosis [PDF]
SummaryValproic acid is considered to be the most well-tolerated antiepileptic drug. However, few cases of neutropenia or leukopenia caused by valproic acid have been reported.
Hsiang-Kuang Tseng +7 more
core +1 more source
Levamisole is a common adulterant found in street‐distributed cocaine. Molecular baskets have been shown to form stable inclusion complexes with both substances. While levamisole inserts its benzene into the basket's cavity, cocaine utilizes its bicyclic ring for encapsulation.
Christopher T. Mortensen +7 more
wiley +1 more source
Agranulocytosis is a serious adverse effect of methimazole (MMI) and propylthiouracil (PTU), and although there have been reports suggesting a dose-dependent incidence in relation to both drugs, the evidence has not been conclusive.
Jaeduk Yoshimura Noh +14 more
doaj +1 more source
Carbamazepine-induced Life-threatening Stevens-Johnson Syndrome and Agranulocytosis: The Maiden Case [PDF]
Stevens-Johnson syndrome is one of the few dermatological emergencies in clinical practice. The syndrome is often secondary to the usage of drugs, of which allopurinol, penicillins, sulfa drugs, ibuprofen, sodium valproate, phenytoin, lamotrigine and ...
A. Avinash +4 more
doaj +1 more source

