Results 51 to 60 of about 21,316 (178)

Agranulocytosis Associated with Topiramate: A Case Report and Review of Published Cases

Case Reports in Hematology, 2018
A 41-year-old female presented to the hospital with sore throat and shortness of breath. She was hypoxic with an oxygen saturation of 87% in room air. Physical examination revealed swollen uvula with exudates.
Saroj Lohani, Niranjan Tachamo, Salik Nazir, Anthony Donato   +3 more
doaj   +1 more source

Fosfomycin-induced agranulocytosis: a case report and review of the literature

BMC Infectious Diseases, 2023
Background The intravenous form of fosfomycin, a bactericide antibiotic used to treat multiresistant bacterial infections is little prescribed. The most common reported adverse effects are hypokaliemia and hypernatremia.
Elodie Matusik, Julien Demanet, Isabelle Alves, Alina Tone, Nicolas Ettahar, Justine Lemtiri, Camille Potey, Sophie Gautier, Fabien Lambiotte, Louise Gaboriau   +9 more
doaj   +1 more source

Annual Research Review: Psychosis in children and adolescents: key updates from the past 2 decades on psychotic disorders, psychotic experiences, and psychosis risk

Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 460-476, April 2025.
Psychosis in children and adolescents has been studied on a spectrum from (common) psychotic experiences to (rare) early‐onset schizophrenia spectrum disorders. This research review looks at the state‐of‐the‐art for research across the psychosis spectrum, from evidence on psychotic experiences in community and clinical samples of children and ...
Ian Kelleher
wiley   +1 more source

Decoding Clozapine-Induced Agranulocytosis: Unraveling Interactions and Mitigation Strategies

Pharmacy
Agranulocytosis represents a severe complication associated with the administration of clozapine. Clozapine is an antipsychotic medication that has demonstrated substantial efficacy in remediating refractory schizophrenia and various other psychiatric ...
Ali Alalawi, Enas Albalawi, Abdullah Aljohani, Abdullah Almutairi, Abdulraouf Alrehili, Areej Albalawi, Ahmed Aldhafiri   +6 more
doaj   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Incidence of aplastic anemia and agranulocytosis in Latin America: the LATIN study

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Aplastic anemia and agranulocytosis are rare but life-threatening disorders, often caused by drugs and other environmental exposures.
Nelson Hamerschlak, Eliane Maluf, Ricardo Pasquini, José Eluf-Neto, Frederico Rafael Moreira, Alexandre Biasi Cavalcanti, Íria Ruriko Okano, Roberto Passeto Falcão, Marimília Teixeira Pita, Sandra Regina Loggetto, Luiz Gastão Rosenfeld, Irene Gyongyvér Heidemarie Lorand-Metze   +11 more
doaj   +1 more source

Dapsone-induced agranulocytosis leading to perianal abscess and death: a case report

Journal of Medical Case Reports, 2011
Introduction Dapsone (diaminodiphenylsulfone) is used for the treatment of intractable skin diseases such as pemphigus and leprosy. The side effects of Dapsone are anemia, leukopenia, and liver dysfunction.
Kitamura Nobuya, Setoguchi Daisuke, Kobe Yoshiro   +2 more
doaj   +1 more source

Association between initial 30‐day cumulative clozapine dose and risk of agranulocytosis: A nationwide register‐based cohort study

Psychiatry and Clinical Neurosciences, EarlyView.
Aims Clozapine‐induced agranulocytosis (CIA) is traditionally considered an idiosyncratic, dose‐independent reaction. However, emerging evidence suggests that clozapine‐related inflammatory events may exhibit dose‐dependent characteristics, leading us to hypothesize that CIA risk may similarly relate to early cumulative exposure.
Yuki Kikuchi, Xue Li, Hiroshi Komatsu, Norio Yasui‐Furukori, Ken Inada, Hiroaki Tomita   +5 more
wiley   +1 more source

Drugs that act on both G protein‐coupled receptors (GPCRs) and kinases: potentiation of effects, side effects and general aspects of drug pleiotropy

British Journal of Pharmacology, Volume 183, Issue 13, Page 3471-3483, July 2026.
Abstract Background A drug designed for a specific target often interacts with multiple targets, either unintentionally or as part of its intended mechanism of action. This has been called pharmacological pleiotropy or polypharmacology. There are key endogenous ligands such as ATP, GABA and glutamate that act on various proteins in humans. Furthermore,
Hampus Ljunggren, Aleksandr Sokolov, Flavio Ballante, Robert Fredriksson, Francisco Lagunas‐Rangel, Alexander S. Hauser, Stefan Knapp, Jörgen Jonsson, Helgi B. Schiöth   +8 more
wiley   +1 more source

Significance of procalcitonin in bacterial infections among acute leukemia patients with post-chemotherapy agranulocytosis [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2017
Introduction/Objective. Bacterial infection caused by the lack of granulocytes that results from the chemotherapy of acute leukemia is the leading cause of death.
Qu Zhigang, Fang Bingmu, Ma Guangli, Jiang Jinhong, Wang Xiaoli, Wang Junnv, Liu Shuping, Wang Xiaoqiu, Liu Yonghua, Zhang Qiaolei   +9 more
doaj   +1 more source