Results 51 to 60 of about 28,792 (217)

A case of antithyroid drug‐induced agranulocytosis from a second antithyroid drugs (ATD) administration in a relapsed Graves' disease patient who was tolerant to the first ATD treatment

Clinical Case Reports, 2018
Key Clinical Message Agranulocytosis is a rare side effect of antithyroid drugs (ATD) that usually develops within the first 3‐6 months after starting treatment.
Hyunsam Kim, Jeongmin Lee, Jeonghoon Ha
doaj   +1 more source

Case Report: Simultaneously Induced Neutropenia and Hemolysis After a Single Metamizole Dose

Drugs in R&D, 2023
Background and objective Metamizole is a non-opioid ampyrone sulfonate compound with potent analgesic, antipyretic, and spasmolytic effects. Agranulocytosis is a rare life-threatening complication of metamizole.
Raphael Allgaier, Arne Kandulski, Karsten Gülow, Lars Maier, Martina Müller, Hauke Christian Tews   +5 more
doaj   +1 more source

Identification of a Novel De Novo Heterozygous SEC61A1 Variant in a Patient With Severe Congenital Neutropenia

Molecular Genetics &Genomic Medicine, Volume 14, Issue 5, May 2026.
Severe congenital neutropenia can be caused by rare SEC61A1 variants. We report a child with SCN showing granulocytic maturation arrest and abnormal immunophenotype, carrying a novel de novo SEC61A1 p.Trp379Arg variant, expanding the phenotypic and genetic spectrum of SEC61A1‐associated SCN.
Zixuan Wang, Hui Jing, Yuhan Chen, Ling Zhong, Jiyun Yang   +4 more
wiley   +1 more source

Lacosamide-induced sinus node dysfunction followed by severe agranulocytosis

BMC Neurology, 2021
Background Lacosamide (LCM) is the antiepileptic drug approved by the U.S. Food and Drug Administration in 2008 that facilitates slow activation of the voltage-gated sodium channels.
Makoto Shibata, Reona Hoshino, Chisato Shimizu, Masayuki Sato, Natsumi Furuta, Yoshio Ikeda   +5 more
doaj   +1 more source

Antithyroid drug-induced agranulocytosis [PDF]

, 1999
Thyrotoxicosis is a common endocrine disorder. Antithyroid drug therapy is the standard treatment for this disease, especially in young women of reproductive age. A serious side effect of antithyroid drug use, however, is agranulocytosis.
Lee, CH, Liang, RHS
core  

The Roles of Macrophage Lineage Cells (MLCs) in Brain Aging

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
This review highlights the critical role of macrophage lineage cells (MLCs), including microglia, border‐associated macrophages (BAMs), and CNS‐infiltrating monocyte‐derived macrophages (MDMs), in brain aging. It explores the drivers and propagation of MLCs senescence and discusses potential therapeutic strategies targeting MLCs senescence.
Qin Qin, Liubin Zhang, Manning Guo, Danli Lu, Yuxin Liu, Zihong Wang, Mengyan Hu, Shisi Wang, Xinmei Kang, Haotong Yi, Wei Qiu, Zhengqi Lu, Wei Cai   +12 more
wiley   +1 more source

Unusual Synchronous Methimazole-Induced Agranulocytosis and Severe Hepatotoxicity in Patient with Hyperthyroidism: A Case Report and Review of the Literature

International Journal of Endocrinology, 2015
Context. To report a patient with hyperthyroidism who developed concurrent occurrence of agranulocytosis and severe hepatotoxicity after taking methimazole (MMI). Case.
Jun Yang, Jun Zhang, Qin Xu, Guo-ping Sheng, Wan-wen Weng, Meng-jie Dong   +5 more
doaj   +1 more source

Considerations of HLA, Renal Failure, Valproic Acid Use, and Current Treatment Guidelines in Clozapine-Induced Agranulocytosis

Case Reports in Psychiatry, 2021
Clozapine, the choice atypical antipsychotic for refractory schizophrenia, schizoaffective disorder, and bipolar disorder, has been shown to reduce positive and negative symptoms of schizophrenia.
Melissa Sussman, Michael Epifania, Derrick Eng, Yun Jae Cho, Richard Steward   +4 more
doaj   +1 more source

Recreational use, analysis and toxicity of tryptamines [PDF]

, 2015
The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs.
Mannocchi, Giulio, Pantano, Flaminia, Romolo, Francesco Saverio, Tittarelli, Roberta   +3 more
core   +1 more source

Altered Brain Tissue Volumes With Valproate Treatment for Schizophrenia

Journal of the Royal Society of New Zealand, Volume 56, Issue 2, April 2026.
Schizophrenia is a debilitating psychiatric condition that affects ≈0.5% of the global population. Some people with schizophrenia do not respond to first‐line antipsychotics and are prescribed clozapine; this is termed treatment‐resistant schizophrenia (TRS).
Thomas Cawood, Olivia K. Harrison, Meghan McIlwain, Robert R. Kydd, Bruce R. Russell   +4 more
wiley   +1 more source